Hill's atopic erythroderma.



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Abstract

Hill's atopic erythroderma is uncommon and is one of the most severe forms of atopic dermatitis, characterized by a universal skin lesion. It most often develops in children under 3 years of age, the frequency of registration is 1.6-8.7% of all cases in this age group, although it can also occur in adolescents.The spread of the island-inflammatory pathological process is accompanied by constant painful itching, symptoms of intoxication and impaired thermoregulation, skin manifestations of vegetative dystonia, lymphadenopathy, often secondary infection, and often occurs with an exacerbation of concomitant allergic respiratory diseases. This article describes the clinical manifestations of Hill's erythroderma that occurred in a 13-year-old child with a burdened personal and family history of atopic diseases against the background of a traumatic situation. During systemic antibiotic therapy, hyposensitizing and antihistamine therapy, local treatment with glucocorticosteroids and emollients, positive dynamics was noted with a gradual regression of the skin pathological process. It is very important to recognize atopic dermatitis as the cause of erythroderma, especially in patients with late onset of the disease, in order to treat it quickly and prevent relapses, educating the patient on an adequate lifestyle and treatment of exacerbations at the first symptoms.

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About the authors

Marina A. Shishkina

Volgograd State Medical University

Author for correspondence.
Email: marinashishkina_derm@mail.ru
ORCID iD: 0000-0001-5479-3075
SPIN-code: 5446-8406

Assistant Lecturer

Russian Federation, 1 Pavshikh Bortsov square, 400131, Volgograd

Svetlana N. Schava

Volgograd State Medical University

Email: snchava@rambler.ru
ORCID iD: 0000-0002-4946-6624
SPIN-code: 7449-7277

MD, Cand. Sci. (Med.), Associate Professor

Russian Federation, Volgograd

References

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  2. Tamrazova OB. Pathogenetic therapy of children suffering from severe forms of atopic dermatitis. RMZH. 2013;2:108-114. (In Russ)
  3. Luger T.A. The best dermatotherapy for glucocorticoids. Therapeutic index. International Society of Dermatologists. 2004; 7: 629-634. (In Deut)
  4. Li J., Zheng HEE. Erythroderma: a clinical and prognostic study. Dermatology. 2012; 225(2):154-162. doi: 10.1159/000342365
  5. Paller A.S., Silverberg J.I., Cork M.Y., Guttman-Yassky E., Lokshin B., Irwin A.D., Kim M.B., Kabashima K., Chen Z., Lu Yu., Bansal A., Rossi A.B., Shabbir A. Efficacy and safety of Dupilumab in patients with erythrodermic atopic dermatitis Follow-up analysis of 6 patients with erythrodermic atopic dermatitis. Randomized clinical trials. YAMA Dermatol. 2023, March 1;159(3):255-266. doi: 10.1001/jama dermatol.2022.6192

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