Melanocytic nevus: Clinical features and colorimetrial evaluation

Cover Page


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

BACKGROUND: An increase in the frequency of registration of skin malformations, benign, precancerous and malignant skin neoplasms requires new approaches to their diagnosis and treatment. The different depth of melanocytic nevi in the epidermis and dermis is reflected in the color of the melanocytic nevus.

AIM: to study the localization, size and intensity of pigmentation of melanocytic nevi depending on their color.

MATERIALS AND METHODS: A clinical and instrumental study of 280 people with melanocytic nevi of various localization was conducted using their colorimetric assessment and dermatoscopic diagnosis. If melanoma was suspected, patients were consulted by an oncologist. The diagnosis of "melanoma" was confirmed histologically.

RESULTS: Melanocytic nevi are more localized on the face than on the abdomen, back or chest, which is confirmed statistically. The largest sizes ― 5.5 mm ― are reached by nevi having a dark brown color, and, consequently, localized in the epidermis above the basal layer, and the smallest ― 2.0 mm ― melanocytic nevi with brown color located in the basal layer of the epidermis, which is also statistically confirmed.

CONCLUSION: The largest sizes ― 5.5 mm ― are reached by nevi having a dark brown color, and, consequently, localized in the epidermis above the basal layer, and the smallest ― 2.0 mm ― melanocytic nevi with brown color located in the basal layer of the epidermis.

Full Text

Restricted Access

About the authors

Mariia V. Sakharova

North-Western State Medical University named after I.I. Mechnikov

Email: dr.marvl@mail.ru
ORCID iD: 0009-0000-3462-2666
SPIN-code: 6791-8256
Russian Federation, 47 Piskarevskii prospekt, 195067 Saint Petersburg

Svetlana V. Klyuchareva

North-Western State Medical University named after I.I. Mechnikov

Email: genasveta@rambler.ru
ORCID iD: 0000-0003-0801-6181
SPIN-code: 9701-1400
Scopus Author ID: 53982986800
ResearcherId: AAH-7581-2019

MD, Dr. Sci. (Med.), Professor

Russian Federation, 47 Piskarevskii prospekt, 195067 Saint Petersburg

Sergey L. Kashutin

Northern State Medical University

Email: sergeycash@yandex.ru
ORCID iD: 0000-0002-2687-3059
SPIN-code: 7623-7216

MD, Dr. Sci. (Med.), Associated Professor

Russian Federation, Arkhangelsk

Mikhail L. Levit

Northern State Medical University

Email: levitml@mail.ru
ORCID iD: 0000-0003-3255-9493
SPIN-code: 4019-7625

MD, Dr. Sci. (Med.), Professor

Russian Federation, Arkhangelsk

Natalya L. Shapchits

Northern State Medical University

Author for correspondence.
Email: nata.shapchits@mail.ru
ORCID iD: 0009-0003-5411-1064
SPIN-code: 5251-7555
Russian Federation, Arkhangelsk

References

  1. Sergeev YuYu, Sergeev VYu, Mordovtseva VV, Beinusov DS. Options of changing the melanocytic formations dermatoscopic picture: Analysis of clinical cases. Effective pharmacotherapy. 2022;18(31):96-100. EDN: JPYRDA doi: 10.33978/2307-3586-2022-18-31-96-100
  2. Mordovtseva VV, Sergeev YuYu. Melanocytic nevi and melanoma of the skin: A practical guide to the diagnosis of melanocytic skin tumours. Ekaterinburg; 2022. 416 p. (In Russ).
  3. De Correa MP. Solar ultraviolet radiation: properties, characteristics and amounts observed in Brazil and South America. An Bras Dermatol. 2015;90(3):297-313. doi: 10.1590/abd1806-4841.20154089
  4. Prasad CP, Mohapatra P, Andersson T. Therapy for BRAFi-Resistant Melanomas: Is WNT5A the Answer? Cancers (Basel). 2015;7(3):1900-1924. doi: 10.3390/cancers7030868
  5. Pizzichetta MA, Massone C, Grandi G, et al. Morphologic changes of acquired melanocytic nevi with eccentric foci of hyperpigmentation (“Bolognia sign”) assessed by dermoscopy. Arch Dermatol. 2006;142(4):479-483. doi: 10.1001/archderm.142.4.479
  6. Aksenenko MB, Ruksha TG. Invasive capacity and proliferative activity of cutaneous melanoma and the epigenetic factor. Russ J Skin Venereal Dis. 2014;(5):4-8. (In Russ). EDN: SYCRTJ
  7. Akhmatova AM, Potekaev NN, Reshetov IV, et al. Early diagnostics of melanoma in dermatological practice. Russ J Clin Dermatol Venereol. 2012;10(2):32-36. EDN: PEJYSJ
  8. Barchuk AA, Podolsky MD, Gaidukov VS, et al. Intelligent distributed system for population screening of cancer. Problems Oncol. 2015;61(4):517-521. EDN: UBZBBB

Supplementary files

Supplementary Files
Action
1. JATS XML
2. Fig. 1. Differentiation of melanocytic nevi by color: light brown (a), brown (b), dark brown (c).

Download (717KB)
3. Fig. 2. The case of detected melanoma: cluster of melanocytic nevi in the dorsal region (a) and enlarged fragment of the detected neoplasm (b).

Download (766KB)
4. Fig. 3. The case of detected melanoma: skin rashes on the skin of the scapular region (a) and an enlarged fragment of the neoplasm (b).

Download (791KB)

Copyright (c) 2024 Eco-Vector



СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 86501 от 11.12.2023 г
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ЭЛ № ФС 77 - 80653 от 15.03.2021 г
.



This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies