Bacterial vaginosis: evaluation of the effectiveness of simultaneous treatment of sexual partners

V. A. Okhlopkov; Охлопков В. А.; S. V. Barinov; Баринов С. В.; Yu. I. Tirskaya; Тирская Ю. И.; Turan Shakhin kyzy Babaeva; Бабаева Туран Шахин кызы; L. B. Sinelnikova; Синельникова Л. Б.; T. V. Terletskaya; Терлецкая Т. В.

doi:10.17816/dv55424

Bacterial vaginosis: evaluation of the effectiveness of simultaneous treatment of sexual partners

Authors: Okhlopkov V.A.¹, Barinov S.V.², Tirskaya Y.I.², Babaeva T.S.³, Sinelnikova L.B.³, Terletskaya T.V.⁴
Affiliations:
1. The Institute of the Federal Scientific and Clinical Center for Resuscitation and Rehabilitation
2. FGBOU VO "Omsk State Medical University" of the Ministry of Health of Russia
3. Perinatal Center BUZ Omsk Region "Regional Clinical Hospital"
4. BUZ Omsk region "Clinical dermatovenerologic dispensary"
Issue: Vol 23, No 6 (2020)
Pages: 422-431
Section: CLINICAL PICTURE, DIAGNOSIS, AND THERAPY OF DERMATOSES
URL: https://rjsvd.com/1560-9588/article/view/55424
DOI: https://doi.org/10.17816/dv55424
ID: 55424

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Abstract

BACKGROUND: Bacterial vaginosis (BV) is one of the most common diseases affecting women of reproductive age. The main problem of BV is the low efficiency of traditional methods of treatment with a frequent recurrence of up to 50%.

MATERIALS AND METHODS: A total of 59 patients were examined and treated with the diagnosis of BV, which was confirmed in accordance with the Amsel criteria. The main group included women with BV and their male partners, whereas the compared group included only women with BV. All women were treated with systemic metronidazole and topical clindamycin, and suppositories with lactic acid were prescribed at the second stage. The men partners were treated systemically with metronidazole and topically with clindamycin.

RESULTS: Gardnerella vaginalis, Atopobium vaginae, and Prevotella were the most commonly identified bacteria in the vaginal discharge. In men, BV-associated bacteria were found in the foreskin of the glans penis and distal urethra. The similarity of the microflora of the genital organs of women and their male partners was determined. In women with sexual partners who were treated 6 months after the therapy, the number of BV-associated bacteria was detected two or more times less frequently than in patients in the comparison group. For the men, the number of complaints and clinical symptoms significantly decreased after the treatment. Significant decreases in Gardnerella vaginalis, Atopobium vaginae, Prevotella spp., Leptotrichia amnionii, and Mobiluncus were achieved in the foreskin and Gardnerella in the urethra. In the main group of women, the frequency of BV recurrences recorded was 2.3 times less than that in the comparison group.

CONCLUSION: The treatment of partners of women with BV effectively reduces the growth of BV-associated bacteria and significantly decreases the frequency of recurrences.

Keywords

bacterial vaginosis, Gardnerella vaginalis, Prevotella, Atopobium vaginae, recurrences, sexual partners

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