Photogallery of diseases of the oral mucosa. Part I

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Abstract

Nowadays, more than 300 diseases of the oral mucosa have been established in the scientific literature. Since pemphigus vulgaris and lichen planus can mimic many other skin conditions it could be difficult to make the diagnosis according only to clinical features. Moreover, pemphigus vulgaris is known to be an autoimmune life-threatening disorder which necessarily need to be treated with high doses of systemic glucocorticoids, whereas lichen planus in some cases can be transformed into squamous cell carcinoma.

The drug associated erythema and the herpes associated erythema multiforme both affect not only the oral mucosa but also the skin, which makes differential diagnosis easier. Nevertheless, in our practice we can encounter only the oral cavity involvement. Previously, Stevens–Johnson syndrome was considered as severe form of erythema multiforme affecting both the skin and the oral mucosa.

Additionally, cheilitis can be observed in patients with atopic dermatitis even in the remission stage.

Furthermore, Melkersson–Rosenthal syndrome is a rare neurological disorder characterized by recurring facial paralysis, swelling of the face and lips, and the development of folds and furrows in the tongue.

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About the authors

Natalya P. Teplyuk

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: Teplyukn@gmail.com
ORCID iD: 0000-0002-5800-4800
SPIN-code: 8013-3256

MD, Dr. Sci. (Med.), Professor

Russian Federation, Moscow

Anfisa A. Lepekhova

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: rjdv@eco-vector.com
Russian Federation, Moscow

Ekaterina V. Grekova

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: grekova_kate@mail.ru
ORCID iD: 0000-0002-7968-9829
SPIN-code: 8028-5545

MD, Cand. Sci. (Med.)

Russian Federation, Moscow

Baira Sh. Damdinova

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Author for correspondence.
Email: baira_d@mail.ru
Russian Federation, Moscow

References

Supplementary files

Supplementary Files
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1. Fig. 1. Pemphigus vulgaris: Bullous elements on the mucous membrane of the oral cavity are not detected, because they quickly transform into erosions located against the background of unchanged mucosa around rashes.

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2. Fig. 2. Pemphigus vulgaris: Erosions on the gums cover the teeth in the form of half-moons.

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3. Fig. 3. Pemphigus vulgaris: With an isolated lesion of the oral mucosa, erosions often occur on the hard palate and the red border of the lips.

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4. Fig. 4. Stevens–Johnson syndrome as a reaction to Biseptol intake.

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5. Fig. 5. Lichen planus: a ― сhanges in the form of a Wickham grid on the mucous membrane of the left cheek; b ― a hyperkeratotic form is formed on the mucous membrane of the right cheek; c ― on the anterior surface of the mucous membrane in upper jaw erosion; d ― on the mucous membrane of the upper jaw erosion, on the mucous and red border of the upper lip changes in the type of Wickham mesh and atrophic form.

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6. Fig. 6. Oral lichen planus of the oral mucosa with transforms into squamous cell carcinoma (confirmed by histological examination).

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7. Fig. 7. Stevens–Johnson syndrome in toxic nephropathy as a reaction to taking nonsteroidal anti-inflammatory drugs for a long time.

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8. Fig. 8. Herpes associated erythema multiforme: a ― erosion with scalloped edges with hyperemia phenomena on the mucous membrane of the hard palate; b ― erosion at the level of the line of closure of the teeth and in the vestibule of the oral cavity; с ― erosion on the mucous membrane of the lower lip.

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9. Fig. 9. Cheilitis in atopic dermatitis.

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10. Fig. 10. Melkersson–Rosenthal syndrome: Combination of recurrent lip edema and unilateral facial nerve paresis.

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ЭЛ № ФС 77 - 80653 от 15.03.2021 г
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