Persistent Chlamidia infection and Reiter's disease, diagnostics and treatment

Reiter's disease (RD) is one of severe manifestations of urogenital chlamydiosis, characterized by combined affection of different organs and systems, most often urogenital organs, eyes and joints. This disorder presents a difficult interdisciplinary problem. Examination of patients with RD and their sexual partners, including persons with confirmed persistent chlamydial infection, needs a wide variety of new methods of laboratory diagnostics. Lymphotropic antibiotic therapy is successfully used in complex therapy. Method of extracorporal photopheresis is effective and pathogenetically validated for treatment of RD. Authors present cases of RD illustrating symptoms, diagnostics and complex therapy of this disease. One of them demonstrates positive effect of complex treatment, confirmed not only by clinical and laboratory examination but also by involution of roentgenologic signs of osteoarticular changes. A case of patient C. presents an interesting retransformation of persistent Chlamydia trachomatis into common types of this microorganism, responding to antibiotic therapy.

urogenital chlamydiosis, Reiter's disease