Minimally invasive combined technique of thread implantation, including the use of lifting threads from polydioxanone and a copolymer of polylactic acid and polycaprolactone and reinforcing threads from 100% polylactic acid

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Abstract

Modern scientific studies demonstrate a direct relationship between a decrease in the quantitative ratio of type I/III collagen in tissues and the severity of age-related changes, the formation of a deformative type of aging and the early development of ptosis of the lower third of the face able to compensate for the reduced ratio of type I/III collagen. In addition, the specificity of the threads used to perform lifting technologies provides an increase in collagen, predominantly of type III, and a relatively small number of them and only a certain lifting route are used. Currently, the clinical efficacy of 100% polylactic acid threads has been proven, which are able to stimulate the synthesis of type I collagen. Thus, the combination of lifting and reinforcing techniques in one procedure is expedient and relevant.

In order to achieve aesthetic and lifting results of thread techniques, as well as to increase the intensity of microcirculation, oxygenation and stimulation of collagenogenesis (including type I), we have developed a method of minimally invasive combined technique of thread implantation, including the use of lifting threads made of polydioxanone and polylactic acid copolymer and polycaprolactone and 100% polylactic acid reinforcing threads.

The minimally invasive technology provides prolongation of the lifting effect; creates the effect of volumization of facial tissues and the supporting dynamic framework in conditions of tissue displacement, and also improves the quality of skin structures by stimulating trophic and oxygenation of tissues, strengthening the collagen framework, increasing the ratio of type I/III collagen, enhancing the production of its own hyaluronic acid and extracellular matrix components.

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About the authors

Ivan I. Gribanov

Burnasyan Federal Medical Biophysical Center; “Beautiful Life” Center for Aesthetic Medicine

Author for correspondence.
Email: jan-caim@mail.ru
ORCID iD: 0000-0002-7906-8731
ResearcherId: X-8375-2018

MD, Cand. Sci. (Med.), Junior Research Associate

Russian Federation, 46, Zhivopisnaya Street, Moscow, 123182; Moscow

References

  1. Smirnova GO, Manturova NE, Topchanova GV, et al. Prediction of the results of aesthetic interventions based on the mechanisms of skin aging and the ratio of collagen types I/III. Fundamental’nye issledovaniya. 2012;(7):191–194. (In Russ).
  2. Golovataya IV, Nerobeev AI, Vasil’eva EY. Morphological study of loose subcutaneous connective tissue around fragments of threads based on 100% polylactic acid in the dynamics of the experiment. Sovershenstvo Profi. 2017. Р. 52–57. (In Russ).
  3. Olisova OYu, Vladimirova EV, Babushkin AM. The skin and the sun. Russian Journal of Skin and Venereal Diseases. 2012;15(6):57–62. (In Russ).
  4. Olisova OYu, Andreeva EV. Once more about hyperpigmentation. Russian Journal of Skin and Venereal Diseases. 2014;17(2):20–24. (In Russ).
  5. Olisova OYu, Gromova SA, Smirennaya VA. Photoaging of the skin: a new view on the problem (lecture). Russian Journal of Skin and Venereal Diseases. 2010;2:58–62. (In Russ).
  6. Dorozhenok IYu, Matyushenko EN, Olisova OYu. Dysmorphophobia in dermatological practice. Russian Journal of Skin and Venereal Diseases. 2014;17(1):42–47. (In Russ).

Supplementary files

Supplementary Files
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1. JATS XML
2. Fig. 1. DG-Lift® lifting threads with frequently positioned molded 3D spikes.

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3. Fig. 2. DG-Lift® reinforcing threads, springs and double springs made of 100% PLLA: а ― Screw modification (PLLA Screw 27G 50 mm, 5-0 USP, 0.1 mm, 80 mm; PLLA Screw 29G 38 mm, 6-0 USP, 0.07 mm, 60 mm); б ― Double Screw modification (PLLA Double Screw 26G-60 mm, 6-0 USP, 0.07 mm, 100 mm).

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4. Fig. 3. Scheme of retrograde zygomatic lifting and reinforcement of the middle and lower third of the face.

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5. Fig. 4. Patient M., 56 years old: а ― before the procedure of combined thread implantation; б ― after the procedure: the degree of satisfaction with the result is 3 points on the GAIS scale (there is a pronounced aesthetic effect).

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6. Fig. 5. Patient А., 44 years old: а ― before the procedure of combined thread implantation; б ― after the procedure: the degree of satisfaction with the result is 3 points on the GAIS scale (there is a pronounced aesthetic effect).

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7. Fig. 6. Patient I., 53 years old: а ― before the procedure of combined thread implantation; б ― after the procedure: the degree of satisfaction with the result is 3 points on the GAIS scale (there is a pronounced aesthetic effect).

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8. Fig. 7. Patient N., 42 years old: а ― before the procedure of combined thread implantation; б ― after the procedure: the degree of satisfaction with the result is 3 points on the GAIS scale (there is a pronounced aesthetic effect).

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9. Fig. 8. Patient V., 43 years old: а ― before the procedure of combined thread implantation; б ― after the procedure: the degree of satisfaction with the result is 3 points on the GAIS scale (there is a pronounced aesthetic effect).

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10. Fig. 9. Patient Е., 50 years old: а ― before the procedure of combined thread implantation; б ― after the procedure: the degree of satisfaction with the result is 2 points on the GAIS scale (there is a moderate aesthetic effect, because the patient has a pronounced volume deficit in the area of the zygomatic arch [lateral SOOF, lateral part of the deep medial fat pack], which is not fully corrected by her own tissues due to movement in the zygomatic direction; in the future, the patient underwent augmentation of the zygomatic areas with a hyaluronic acid filler, which gave maximum satisfaction with the result obtained).

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11. Fig. 10. Patient Yu., 49 years old: а ― before the procedure of combined thread implantation; б ― after the procedure: the degree of satisfaction with the result is 3 points on the GAIS scale (there is a pronounced aesthetic effect).

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12. Fig. 11. Patient N., 47 years old: а ― before the procedure of combined thread implantation; б ― after the procedure: the degree of satisfaction with the result is 2 points on the GAIS scale (there is a moderate aesthetic effect, because the patient has a pronounced volume deficit in the area of the deep paragrushoid space of the face and the medial part of the deep fat package, in connection with which the pronounced nasolabial fold is not completely corrected only by moving tissues to the temporal-zygomatic region; in the future, the patient underwent volumization of these areas with a hyaluronic acid filler, which gave maximum satisfaction with the result obtained).

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