Dermatoscopic patterns in vitiligo

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Abstract


BACKGROUND: Vitiligo is a chronic disease characterized by the appearance of depigmented spots on various parts of the body. Bright white spots on the skin cause the psychosocial maladjustment of individuals with this condition. To date, modern medicine lacks effective methods for the objective and accessible diagnosis of this disease. However, research methods, such as dermatoscopy, can be useful in diagnosing vitiligo and determining its stage.

AIM: This study aimed to identify the main dermatoscopic patterns of vitiligo in association with the activity of the process.

MATERIALS AND METHODS: To participate in the study, 63 patients with diagnosed vitiligo were examined. Patients participating in the study were divided into three groups: 34 patients with progressive course, 11 with stable condition, and 18 at the stage of repigmentation. A dermatoscopic examination was performed using a Delta 20T dermatoscope. Statistical processing of research materials was carried out using the SPSS statistics software package.

RESULTS: The most significant changes were found in the perifollicular area. Progressive vitiligo was characterized by perifollicular pigmentation (91.2%), an altered pigment network (97.1%), blurred spot border (94.1%), and specific structures, such as star-like formations and a “comet tail.” The stable vitiligo was characterized by perifollicular depigmentation (81.8%) and a sharp border of the spots (72.7%). For the stage of repigmentation, marginal hyperpigmentation (100%), perifollicular depigmentation (72.2%), blurred spot border (77.8%), and “islets of pigmentation” (77.8%) were observed.

CONCLUSION: The diagnostic dermatoscopic patterns of vitiligo have been developed for the first time, and their value has been proven. Dermatoscopy is a promising non-invasive auxiliary method used to diagnose vitiligo and determine the stage of the disease.


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About the authors

Alina Yu. Davletshina

The State Education Institution of Higher Professional Training The First Sechenov Moscow State Medical University under Ministry of Health of the Russian Federation

Author for correspondence.
Email: davletshinalina@gmail.com
ORCID iD: 0000-0002-7496-7551

Russian Federation, Moscow

Graduate student of the department of skin and venereal diseases named after V.A. Rakhmanova

Konstantin M. Lomonosov

Skin and Veneral desease Department of I.M. Sechenov First Moscow State Medical University

Email: davletshinalina@gmail.com

Russian Federation, Moscow

Doctor of Medical Sciences, Professor of the department of skin and venereal diseases named after V.A. Rakhmanova

References

  1. Krüger C, Schallreuter KU. A review of the worldwide prevalence of vitiligo in children/adolescents and adults. Int J Dermatol. 2012 Oct;51(10):1206-12. doi: 10.1111/j.1365-4632.2011.05377.x
  2. Karagaiah P, Valle Y, Sigova J, Zerbinati N, Vojvodic P. Emerging drugs for the treatment of vitiligo. Expert Opin Emerg Drugs. 2020;25(1):7-24. doi: 10.1080/14728214.2020.1712358
  3. Misri R, Pande S, Khopkar U. Confocal laser microscope. Indian J Dermatol Venereol Leprol. 2006 Sep-Oct;72(5):394-7. doi: 10.4103/0378-6323.27769
  4. Gilje O, O’Leary PA, Baldes EY. Capillary microscopic examination in skin disease. Arch Dermatol 1958;(68):136-45.
  5. Ianoși SL, Forsea AM, Lupu M, Ilie MA, Zurac S, Boda D, et al. Role of modern imaging techniques for the in vivo diagnosis of lichen planus. Exp Ther Med. 2019;17(2):1052-60. doi: 10.3892/etm.2018.6974
  6. Vos MHE, Nguyen KP, Van Erp PEJ, Van de Kerkhof PCM, Driessen RJB, Peppelman M. The value of (video)dermoscopy in the diagnosis and monitoring of common inflammatory skin diseases: a systematic review. Eur J Dermatol. 2018;28(5):575-96. doi: 10.1684/ejd.2018.3396
  7. Zalaudek I, Conforti C, Guarneri F, Vezzoni R, Deinlein T, Hofmann-Wellenhof R, et al. Clinical and dermoscopic characteristics of congenital and non-congenital nevus-associated melanomas. J Am Acad Dermatol. 2020;83(4)1080-7. doi: 10.1016/j.jaad.2020.04.120
  8. Mazzilli S, Cosio T, Diluvio L, Vollono L, Gonzalez S, Di Prete M, et al. Dermoscopy and reflectance confocal microscopy in the diagnosis and management of nail fold squamous cell carcinoma. J Med Life. 2020;13(1):107-11. doi: 10.25122/jml-2019-0129
  9. Neynaber S, Wolff H. Diagnosis of scabies with dermoscopy. CMAJ. 2008;178(12):1540-1. doi: 10.1503/cmaj.061753
  10. Cestari TF, Martignago BF. Scabies, pediculosis, bedbugs, and stinkbugs: uncommon presentations. Clin Dermatol. 2005;23(6):545-54
  11. Piccolo V. Update on dermoscopy and infectious skin diseases. Dermatol Pract Concept. 2019;10(1):e2020003. doi: 10.5826/dpc.1001a03
  12. Cardoso AEC, Cardoso AEO, Talhari C, Santos M. Update on parasitic dermatoses. An Bras Dermatol. 2020;95(1):1-14. doi: 10.1016/j.abd.2019.12.001
  13. Golinska J, Sar-Pomian M, Rudnicka L. Dermoscopic features of psoriasis of the skin, scalp and nails – a systematic review. J Eur Acad Dermatol Venereol. 2019;33(4):648-60. doi: 10.1111/jdv.15344
  14. Jha AK, Lallas A, Sonthalia S, Jhakar D, Udayan UK, Chaudhary RKP. Differentiation of pityriasis rubra pilaris from plaque psoriasis by dermoscopy. Dermatol Pract Concept. 2018;8(4):299-302. doi: 10.5826/dpc.0804a10
  15. Nwako-Mohamadi MK, Masenga JE, Mavura D, Jahanpour OF, Mbwilo E, Blum A. Dermoscopic features of psoriasis, lichen planus, and pityriasis rosea in patients with skin type IV and darker attending the regional dermatology training centre in Northern Tanzania. Dermatol Pract Concept. 2019;9(1):44-51
  16. Garcia-Garcia B, Munguia-Calzada P, Auban-Pariente J, Argenziano G, Vazquez-Lopez F. Dermoscopy of lichen planus: Vascular and Wickham striae variations in the skin of colour. Australas J Dermatol. 2019;60(4):301-4. doi: 10.1111/ajd.13052
  17. Feng H, Gutierrez D, Rothman L, Meehan S, Sicco KL. Lichen planus pigmentosus. Dermatol Online J. 2018;24(12):13030/qt0wz1v2kd.
  18. Behera B, Remya R, Chandrashekar L, Thappa DM, Gochhait D, Dey B. Wickham’s striae-like appearance in a case of nodular Kaposi’s sarcoma: A dermoscopic pitfall. Indian J Dermatol Venereol Leprol. 2017;83(5):604-6. doi: 10.4103/ijdvl.IJDVL_973_16
  19. Sgouros D, Apalla Z, Ioannides D, Katoulis A, Rigopoulos D, Sotiriou E, et al. Dermoscopy of common inflammatory disorders. Dermatol Clin. 2018;36(4):359-68. doi: 10.1016/j.det.2018.05.003
  20. Gulseren D, Hofmann-Wellenhof R. Evaluation of dermoscopic criteria for seborrheic keratosis on non-polarized versus polarized dermoscopy. Skin Res Technol. 2019;25(6):801-4. doi: 10.1111/srt.12721
  21. Thatte SS, Khopkar US. The utility of dermoscopy in the diagnosis of evolving lesions of vitiligo. Indian J Dermatol Venereol Leprol. 2014;80(6):505-8. doi: 10.4103/0378-6323.144144

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