Clinical efficacy and characteristics of immunological changes in patients with psoriasis following the combined use of sulfide peloids from Lake Saki

Marina Yu. Kuznetsova; Кузнецова Марина Юрьевна; O. A. Pritulo; Притуло О. А.; I. A. Dovgan; Довгань И. А.; O. N. Sokolova; Соколова О. Н.

doi:10.17816/dv48909

Clinical efficacy and characteristics of immunological changes in patients with psoriasis following the combined use of sulfide peloids from Lake Saki

Authors: Kuznetsova M.Y.¹, Pritulo O.A.¹, Dovgan I.A.², Sokolova O.N.²
Affiliations:
1. Medical Academy n.a. V.I. Vernadsky Crimean Federal University
2. N.I. Pirogov’s Saki Military Clinical Sanatorium
Issue: Vol 23, No 5 (2020)
Pages: 303-311
Section: CLINICAL PICTURE, DIAGNOSIS, AND THERAPY OF DERMATOSES
URL: https://rjsvd.com/1560-9588/article/view/48909
DOI: https://doi.org/10.17816/dv48909
ID: 48909

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Abstract

BACKGROUND: Psoriasis is a common disease, and many of its forms are resistant to treatment.

AIM: This study aimed to analyze the effects of complex treatment with Lake Saki sulfide peloids on the clinical and immunological parameters patients with psoriasis.

MATERIALS AND METHODS: The study included 90 patients with steady-state psoriasis of mild or moderate severity (51 men and 39 women) aged 23–65 (mean age 37.3 ± 12.7) years, who received treatment at the N.I. Pirogov Saki Military Clinical Health Resort of the Russian Ministry of Defense. The control group consisted of 30 apparently healthy volunteers.

RESULTS: Taking into account the clinical and immunological parameters of patients with mild and moderate psoriasis, we have developed a complex differentiated method of treatment using Lake Saki peloids and brine supplemented with an alpha-lipoic acid preparation.

CONCLUSION: The presented complex method of peloid balneotherapy in combination with alpha-lipoic acid preparation intensifies the 14-day course of sanatorium-resort treatment, increases the duration of remission, and enhances the quality of life of patients with mild-to-moderate psoriasis.

Keywords

psoriasis, dermatological indices, immune and morphological changes, peloids, brine from the Lake Saki, alpha-lipoic acid

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About the authors

Marina Yu. Kuznetsova

Medical Academy n.a. V.I. Vernadsky Crimean Federal University

Author for correspondence.
Email: mary.kuznetz2013@yandex.ru
ORCID iD: 0000-0001-9227-4751

MD, assistant of S.I. Georgievsky Department of Dermatovenereology and Cosmetology

Russian Federation, Simferopol

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