Atrophoderma vermiculatum: clinical presentation features, differential diagnosis and treatment

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Atrophoderma vermiculata is a rare, benign, follicular dermatosis localized in an esthetically important facial skin zone, which results in superficial scars formation. The disease usually occurs at the age of 5–12 years and may be autosomal-dominantly inherited. This type of dermatosis may be associated with other congenital abnormalities and some hereditary diseases, such as Marfan syndrome, neurofibromatosis, congenital heart defects, and mental retardation similar to Down’s syndrome. The authors also analyze the typical clinical presentations of atrophoderma vermiculata, from their own clinical experience, conduct a detailed analysis of differential diagnosis with other dermatoses, and provide contemporary therapeutic methods and approaches to this skin disorder.

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About the authors

O. A. Vishnevskaya

Ramenskoye Central City Clinical Hospital

ORCID iD: 0000-0001-8036-1380

Department of Dermatology

Russian Federation, Moscow region, Ramenskoye, 140100

L. M. Shnakhova

First Moscow State Medical University (Sechenov University)

Author for correspondence.
ORCID iD: 0000-0003-3000-0987

Department of Dermatology and Venerology of I.M. Sechenov

Russian Federation, Moscow, 119991


  1. Das A., Podder I. Atrophoderma vermiculatum. Indian Pediatr. 2014; 51(8): 679.
  2. Luria R.B., Conologue T. Atrophoderma vermiculatum: A case report and review of the literature on keratosis pilaris atrophicans. Cutis. 2009; 83(2): 83-6.
  3. Oliver E.A., Bluefarb S.M. Atrophoderma vermiculatum (?) Arch Derm Syphilol. 1946; 53: 192.
  4. Jansen T., Sander C., Altmeyer P. Atrophodermia vermiculata: case report and review of the literature. J Eur Acad Dermatol Venereol. 2003; 17(1): 70-2. doi: 10.1046/j.1468-3083.2003.00517.x.
  5. Frosch P.J., Brumage M.R., Schuster-Pavlovic C., Bersch A.
  6. Atrophoderma vermiculatum. Case reports and review. J Am Acad Dermatol. 1988; 18(3): 538-42. doi: 10.1016/s0190-9622(88)70077-8.
  7. Thomas J., Muthuswami T.C. Atrophoderma vermiculatum in a father and son. Indian J Dermatol Venereol Leprol. 1987; 53(6): 355-6.
  8. Wang J.F., Orlow S.J. Keratosis pilaris and its subtypes: associations, new molecular and pharmacologic etiologies, and therapeutic options. Am J Clin Dermatol. 2018; 19(5): 733-57.
  9. Hwang S., Schwartz R.A. Keratosis pilaris: a common follicular hyperkeratosis. Cutis. 2008; 82(3): 177-80.
  10. Lateef A., Schwartz R.A. Keratosis pilaris. Cutis. 1999; 63(4): 205-7.
  11. Freer G., Pistello M. Varicella-zoster virus infection: natural history, clinical manifestations, immunity and current and future vaccination strategies. New Microbiol. 2018; 41(2): 95-105.
  12. Boen M., Jacob C. A review and update of treatment options using the acne scar classification system. Dermatol Surg. 2019; 45(3): 411-22.
  13. Iwanami K., Nakai M., Kitamura K. Bazex syndrome.
  14. Intern Med. 2018; 57(10): 1501-2. doi: 10.2169/internalmedicine.9771-17.
  15. Gerbig A. Treating keratosis pilaris. J Am Acad Dermatol. 2002;47(3):457. doi: 10.1067/mjd.2002.122733.
  16. Ramos-e-Silva M., Pirmez R. Red face revisited: Disorders of hair growth and the pilosebaceous unit. Clin Dermatol. 2014; 32(6): 784-99. doi: 10.1016/j.clindermatol.2014.02.018.
  17. Kootiratrakarn T., Kampirapap K., Chunhasewee C. Epidermal permeability barrier in the treatment of keratosis pilaris. Dermatol Res Pract. 2015; 2015: 205012. doi: 10.1155/2015/205012.
  18. Arnold A.W., Buechner S.A. Keratosis pilaris and keratosis pilaris atrophicans faciei J Dtsch Dermatol Ges. 2006; 4(4): 319-23. doi: 10.1111/j.1610-0387.2006.05933.x.
  19. Garwood J.D. Keratosis pilaris. Am Fam Physician. 1978; 17(2): 151-2.

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