Urticaria-like rash in a patient with COVID-19 associated pneumonia of moderate severity: aspects of pathogenesis

Cover Page


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

In mid 2020, the number of new coronavirus (COVID-19) cases has exceeded globally six million. The clinical manifestations of COVID-19 infection are numerous mostly causing damage to the bronchopulmonary system in the form of a dry cough, rhinitis, dyspnea, fever, myalgia, and general weakness. Skin manifestations of COVID-19 are rare and currently include five types of skin lesions occurring during the infection process, which are reliably recorded in only a limited number of case reports and certain analytical publications. This article describes the clinical case of a 28-year-old patient with urticaria-like disseminated rash and confirmed COVID-19-associated pneumonia.

Full Text

Restricted Access

About the authors

Ekaterina V. Orlova

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Author for correspondence.
Email: orlovaderm@yandex.ru

Department of Dermatology and Venereology

Russian Federation, 119991, Moscow

L. M. Smirnova

First Moscow State Medical University (Sechenov University)

Email: orlovaderm@yandex.ru

Department of Dermatology and Venereology of I.M. Sechenov

Russian Federation, Moscow, 119991

N. I. Melikova

First Moscow State Medical University (Sechenov University)

Email: orlovaderm@yandex.ru

Department of Dermatology and Venereology of I.M. Sechenov

Russian Federation, Moscow, 119991

K. Yu. Popova

First Moscow State Medical University (Sechenov University)

Email: orlovaderm@yandex.ru

Department of Dermatology and Venereology of I.M. Sechenov

Russian Federation, Moscow, 119991

References

  1. Li Q., Guan X., Wu P., Wang X., Zhou L., Tong Y., et al. Early transmission dynamics in Wuhan, China, of novel coronavirus –
  2. infected pneumonia. N Engl J Med. 2020; 382(13): 1199-207.
  3. Zhu N., Zhang D., Wang W., Li X., Yang B., Song J., et al.; China Novel Coronavirus Investigating and Research Team. A novel coronavirus from patients with pneumonia in China, 2019.
  4. N. Engl. J. Med. 2020; 382(8): 727-33.
  5. World Health Organization Press Conference. The World Health Organization (WHO) Has Officially Named the Disease Caused by the Novel Coronavirus as COVID-19. [Available at: https://www.who.int/emergencies/diseases/novel-coronavirus-2019. Accessed on 11 Febr 2020].
  6. Gorbalenya A.E., Baker S.C., Baric R.S., de Groot R.J., Drosten C., Gulyaeva A.A., et al. Severe acute respiratory syndrome-related coronavirus: The species and its viruses – a statement of the Coronavirus Study Group. BioRxiv. 2020. [Available at: https://www.biorxiv.org/content/10.1101/2020.02.07.937862v1. Accessed on 11 Febr 2020]. DOI: https://doi.org/10.1101/2020.02.07.937862
  7. The World Health Organization (WHO) Coronavirus Disease (COVID-2019) Dashboard. [Available on: https://covid19.who.int. Access on 30 May 2020].
  8. Temporary Methodical Recommendations “Prevention, diagnosis and treatment of new coronavirus infection (COVID-19)” of the Ministry of Health of the Russian Federation (Ver. 6, 24.04.2020). Available on: https://www.rosminzdrav.ru/ministry/med_covid19. Access on 30 April 2020]. (in Rissian)
  9. Guan W.J., Ni Z.Y., Hu Y., Liang W.H., Ou C.Q., He J.X., et al.; China Medical Treatment Expert Group for Covid-19. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020; 382(18): 1708-20.
  10. Hedou M., Carsuzaa F., Chary E., Hainaut E., Cazenave-Roblot F., Masson Regnault M. Comment on “Cutaneous manifestations in COVID-19: a first perspective” by Recalcati S. J Eur Acad Dermatol Venereol. 2020. doi: 10.1111/jdv.16519. Online ahead of print.
  11. Mahe A., Birckel E., Krieger S., Merklen C., Bottlaender L. A distinctive skin rash associated with Coronavirus Disease 2019? J Eur Acad Dermatol Venereol. 2020. DOI: https://doi.org/10.1111/jdv.16471. Online ahead of print.
  12. Mollaret G. Covid-19: les dermatologues appellant à la vigilance sur les acrosyndromes et érythèmes faciaux. Le quotidien du medecin. 2020. [Available on: https://www.lequotidiendumedecin.fr/specialites/dermatologie/covid-19-les-dermatologues-appellent-la-vigilance-sur-les-acrosyndromes-et-erythemes-faciaux. Access on 30 April 2020].
  13. Redford T., Al-Dissi A.N. Feline infectious peritonitis in a cat presented because of papular skin lesions. Can Vet J. 2019; 60(2): 183-185.
  14. Casas C.G., Catala A., Hernandez Carretero G., Rodriguez-Jimenez P., Fernandez Nieto D., Rodríguez-Villa Lario A., et al. Classification of the cutaneous manifestations of COVID-19: A Rapid Prospective Nationwide Consensus Study in Spain with 375 cases. Br J Dermatol. 2020. doi: 10.1111/bjd.19163. Online ahead of print.
  15. Gianotti R., Zerbi P., Dodiuk-Gad R.P. Clinical and histopathological study of skin dermatoses in patients affected by COVID-19 infection in the Northern Part of Italy. J Dermatol Sci. 2020; S0923-1811(20)30143-2. doi: 10.1016/j.jdermsci.2020.04.007. Online ahead of print.
  16. Sachdeva M., Gianotti R., Shah M., Lucia B., Tosi D., Veraldi S., et al. Cutaneous manifestations of COVID-19: Report of three cases and a review of literature. J Dermatol Sci. 2020.
  17. doi: 10.1016/j.jdermsci.2020.04.011. Online ahead of print.
  18. Manalo I.F., Smith M.K., Cheeley J., Jacobs R. A dermatologic manifestation of COVID-19: transient livedo reticularis,
  19. J. Am. Acad. Dermatol. 2020. DOI: https://dx.doi.org/10.1016/j.jaad.2020.04.018. [Available on: https://www.researchgate.net/publication/340559100_A_Dermatologic_Manifestation_of_COVID-19_Transient_Livedo_Reticularis]
  20. Magro C., Mulvey J., Berlin D., Nuovo G., Salvatore S., Harp J., et al. Complementary associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases. Transl Res. 2020; S1931-5244(20)30070-0. doi: 10.1016/j.trsl.2020.04.007. Online ahead of print.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2020 Eco-Vector



СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 86501 от 11.12.2023 г
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ЭЛ № ФС 77 - 80653 от 15.03.2021 г
.



This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies