No 1 (2017)
- Year: 2017
- Published: 28.02.2017
- Articles: 11
- URL: https://rjsvd.com/0869-7922/issue/view/9719
- DOI: https://doi.org/10.36946/0869-7922-2017-1
Full Issue
Articles
Actual issues of teaching basic priciples of preventive toxicology to specialists of medical and prophylaсtic profile
Abstract



Toxicological monitoring of causes of acute poisonings of chemical etiology in the Russian Federation
Abstract



A structural analysis of acute exotoxicoses in people of elderly and senile age
Abstract



ENDOSCOPIC DIAGNOSTICS AND THERAPY OF CHEMICAL BURNS IN RESPIRATORY TRACTS
Abstract



INVESTIGATIONS INTO NANOSCALE PARTICLES AS PART OF INDUSTRIAL AEROSOLS AND PARTICULATE MATTER IN THE AIR OF WORKING AREA
Abstract



TOXICOLOGICAL AND HYGIENE CHARACTERIZATION OF SOME METAL-CONTAINING NANOPARTICLES AT VARIOUS EXPOSITION METHODS: BIOACCUMULATION AND MORPHOFUNCTIONAL EXPOSURE FEATURES
Abstract



CYTOME ANALYSIS OF EFFECTS OF GENOMIC INSTABILITY INDUCED BY DIFFERENTLY SIZED SILVER NANOPARTICLES IN HUMAN WHOLE BLOOD CULTURE
Abstract
A high bactericidal activity of silver nanoparticles (NHS) suggests the possibility of their use in the preparation of drinking water. On the example of human peripheral blood lymphocytes cultured in micronucleus test with cytochalasin B, effects of genome instability were investigated in a concentration range of 0.005-5.0 mg / l of silver nanoparticles (NHS) with a size of 14.3 ± 0.2 nm (Ag14) and 100.0 ± 11.0 nm (AG100), stabilized with gum acacia and for comparison , those of Ag2SO4 (silver ions). In the same range of concentrations . All substances were suspended or dissolved in drinking water.The results showed that the NPS had genotoxic and cytotoxic effects that made them unsuitable to improve the quality of drinking water. Effects of genome instability determined by the frequency of dividing cells with micronuclei and nucleoplasmic bridges, as well as inhibition of mitotic activity, decrease of proliferative activity and increasing duration of the cell cycle came down in series of Ag2SO4 >> Ag100 >> Ag14. However, frequency rise of asymmetric 3-nucleated cells due to aneuploidy induction was the most characteristic of Ag14 particles.



ANALYSIS OF FUNCTIONAL CHANGES IN THE RODENTS CENTRAL NERVOUS SYSTEM AT A SINGLE UPTAKE OF DEPLETED URANIUM OXIDE MIXED WITH WATER
Abstract



GENDER SPECIFIC CHANGES IN MOUSE BLOOD ESTRERASE PROFILE AT THE ACUTE INTOXICATION BY 2-(О-CRESYL)-4Н-1,3,2-BENZODIOXAPHOSPHORIN-2-OXIDE
Abstract



CHANGES IN REPRODUCTIVE POTENTIAL, SURVIVAL AND METABOLIC ACTIVITY IN TWO SUCCESSIVE GENERATIONS OF DAPHNIA MAGNA IN THE PIPERONYL BUTOXIDE MEDIUM
Abstract



MICROORGANISM BACILLUS KOMAGATAELLA (PICHIA) PASTORIS ВKПМ Y-4225
Abstract


