Email this article STRATEGY AND TACTICS OF TNE PESTICIDE MUTAGENECITY ASSESSMENT
- Authors: Rakitskii V.N.1, Revazova Y.A.1, Ilyushina N.A.1
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Affiliations:
- The Federal Budgetary Science Institution «F.F. Erisman Federal Scientific Centre of Hygiene», Federal Service for Surveillance on Consumer Rights and Human Well-being (Rospotrebnadzor)
- Issue: No 5 (2015)
- Pages: 10-12
- Section: Articles
- Published: 01.10.2015
- URL: https://rjsvd.com/0869-7922/article/view/641328
- DOI: https://doi.org/10.15690/vramn508
- ID: 641328
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Abstract
Toxicological and hygienic risk assessment of pesticides widespread use to human health includes the analysis of their mutagenic activity as a compulsory part. A risk assessment strategy of pesticides mutagenic impacts based on their hygiene classification by mutagenicity criterion is presented. Changes in tactical approaches having occurred recently are considered. A set of methods harmonized with international requirements for assessment of mutagenic activity of pesticides, main metabolites and components of their preparative forms is recommended. It allows to determine a hazard class by a given harmful index. Issues are considered in respect to the usage of short-time testing for assessment of generic pesticides mutagenicity, determination of preparative forms potential genotoxicity and forecasting carcinogenic properties of substances under consideration.
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About the authors
Valery Nikolaevich Rakitskii
The Federal Budgetary Science Institution «F.F. Erisman Federal Scientific Centre of Hygiene», Federal Service for Surveillance on Consumer Rights and Human Well-being (Rospotrebnadzor)
Author for correspondence.
Email: noemail@neicon.ru
Академик РАН, профессор, и.о. директора ФБУН «Федеральный научный центр гигиены им.Ф.Ф.Эрисмана» Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека, 141014, Московская область, г. Мытищи, Российская Федерация
e-mail: pesticide@yandex.ru
Russian FederationYulia Anatolevna Revazova
The Federal Budgetary Science Institution «F.F. Erisman Federal Scientific Centre of Hygiene», Federal Service for Surveillance on Consumer Rights and Human Well-being (Rospotrebnadzor)
Email: noemail@neicon.ru
Доктор биологических наук, профессор, заслуженный деятель науки РФ, ведущий научный сотрудник отдела генетической токсикологии ФБУН Федерального бюджетное учреждение науки «Федеральный научный центр гигиены им.Ф.Ф.Эрисмана» Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека, 141014, Московская область, г. Мытищи, Российская Федерация
e-mail: Revazova013@gmail.com
Russian FederationNatalia Alexeevna Ilyushina
The Federal Budgetary Science Institution «F.F. Erisman Federal Scientific Centre of Hygiene», Federal Service for Surveillance on Consumer Rights and Human Well-being (Rospotrebnadzor)
Email: noemail@neicon.ru
Кандидат биологических наук, заведующий отделом генетической токсикологии ФБУН «Федеральный научный центр гигиены им.Ф.Ф.Эрисмана» Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека, 141014, Московская область, г. Мытищи, Российская Федерация
e-mail: Ilyushina-na@mail.ru
Russian FederationReferences
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