REVISION OF MAC IN THE AIR OF THE WORKING AREA OF TEREPHTHALIC ACID

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Abstract

The results of our own and foreign studies have shown the absence of sensitizing properties of terephthalic acid, and therefore there was a need to review the current hygienic standard – MAC – in the air of the working area and change the hazard class of the substance. The materials of the German Research Community (DFG) were used for substantiation of MAC. Recommended MAC in the air of working area is set at 5 mg/m3 (maximum single), a mixture of vapors and aerosol, hazard class 3.

About the authors

K. K. Khamidulina

Russian Register of Potentially Hazardous Chemical and Biological Substances of Rospotrebnadzor; Russian Medical Academy of Continuous Professional Education, RF Ministry of Health

Author for correspondence.
Email: director@rosreg.info

Khamidulina Khalidya Khizbulaevna

121087, Moscow

Russian Federation

A. S. Radilov

Research Institute of Hygiene, Occupational Pathology and Human Ecology of the Federal Medical and Biological Agency

Email: radilov@rihophe.ru

Radilov Andrey Stanislavovich

188663, Leningrad region, Vsevolozhsky district, Kuzmolovsky

Russian Federation

S. A. Dulov

Research Institute of Hygiene, Occupational Pathology and Human Ecology of the Federal Medical and Biological Agency

Email: niigpech@rihophe.ru

Dulov Sergey Anatolevich

188663, Leningrad region, Vsevolozhsky district, Kuzmolovsky

Russian Federation

A. V. Zemlyanoy

Research Institute of Hygiene, Occupational Pathology and Human Ecology of the Federal Medical and Biological Agency

Email: al-zem@yandex.ru

Zemlyanoy Alexander Vasilevich

188663, Leningrad region, Vsevolozhsky district, Kuzmolovsky

Russian Federation

P. P, Beltyukov

Research Institute of Hygiene, Occupational Pathology and Human Ecology of the Federal Medical and Biological Agency

Email: beltiukov@gpech.ru

Beltyukov Petr Petrovich

188663, Leningrad region, Vsevolozhsky district, Kuzmolovsky

Russian Federation

E. V. Vivulanets

Research Institute of Hygiene, Occupational Pathology and Human Ecology of the Federal Medical and Biological Agency

Email: vivulanets@gpech.ru

Vivulanets Elena Valerievna

188663, Leningrad region, Vsevolozhsky district, Kuzmolovsky

Russian Federation

S. A. Kucherskoy

Research Institute of Hygiene, Occupational Pathology and Human Ecology of the Federal Medical and Biological Agency

Email: seamen20@list.ru

Kucherskoy Semen Alexandrovich

188663, Leningrad region, Vsevolozhsky district, Kuzmolovsky

Russian Federation

M. F. Shishonok

Research Institute of Hygiene, Occupational Pathology and Human Ecology of the Federal Medical and Biological Agency

Email: 8ambulance@mail.ru

Shishonok Maxim Fedorovich

188663, Leningrad region, Vsevolozhsky district, Kuzmolovsky

Russian Federation

E. V. Tarasova

Russian Register of Potentially Hazardous Chemical and Biological Substances of Rospotrebnadzor

Email: secretary@rosreg.info

Tarasova Elena Vladimirovna

121087, Moscow

Russian Federation

A. S. Proskurina

Russian Register of Potentially Hazardous Chemical and Biological Substances of Rospotrebnadzor; Russian Medical Academy of Continuous Professional Education, RF Ministry of Health

Email: proskurina-as@rosreg.info

Proskurina Angelina Sergeevna

121087, Moscow

Russian Federation

A. R. Egiazaryan

Russian Register of Potentially Hazardous Chemical and Biological Substances of Rospotrebnadzor

Email: secretary@rosreg.info

Egiazaryan Anna Rafaelovna

121087, Moscow

Russian Federation

I. V. Zamkova

Russian Register of Potentially Hazardous Chemical and Biological Substances of Rospotrebnadzor

Email: secretary@rosreg.info

Zamkova Irina Valentinovna

121087, Moscow

Russian Federation

E. V. Dorofeeva

Russian Register of Potentially Hazardous Chemical and Biological Substances of Rospotrebnadzor

Email: secretary@rosreg.info

Dorofeeva Ekaterina Valentinovna

121087, Moscow

Russian Federation

E. A. Rinchindorzhieva

Russian Register of Potentially Hazardous Chemical and Biological Substances of Rospotrebnadzor

Email: secretary@rosreg.info

Rinchindorzhieva Ekaterina Anatolievna

121087, Moscow

Russian Federation

D. N. Rabikova

Russian Register of Potentially Hazardous Chemical and Biological Substances of Rospotrebnadzor; Russian Medical Academy of Continuous Professional Education, RF Ministry of Health

Email: secretary@rosreg.info

Rabikova Dinara Nurullaevna

121087, Moscow

Russian Federation

S. A. Shvykina

Russian Register of Potentially Hazardous Chemical and Biological Substances of Rospotrebnadzor;

Email: secretary@rosreg.info

Shvykina Svetlana Aleksandrovna

121087, Moscow

Russian Federation

References

  1. Izmerov N.F., Sanotsky, I.V., Sidorov, K.K. Toxicometric parameters of industrial toxic chemicals under single exposure. Handbook-M., Medicine, 1977. - P. 145 (in Russian).
  2. Pohanish R.P. Sittig’s Handbook of Toxic and Hazardous Chemicals and Carcinogens / R.P. Pohanish // Elsevier Science. - ISBN 9781437778700. - 2011. – 3096 p.
  3. CCOHS RTECS. Canadian Centre Occupational Health and Safety, Registry of Toxic Effects of Chemical Substances, 2020.
  4. Harmful substances in industry. Organic substances. ed. Lazarev N.V., Levina E.N. - L., Chemistry, 1976. - Vol. II. - P. 31 (in Russian).
  5. Sheftel V.O. Harmful substances in plastics. Handbook. - M., Chemistry, 1991. - P. 188 (in Russian).
  6. Research report «Determination of the allergenic properties of terephthalic acid». Research Institute of Hygiene, Occupational Pathology and Human Ecology of the Federal Medical and Biological Agency, 2020. – 56 p. (in Russian).
  7. ECHA. European Chemicals Agency’s Dissemination portal with information on chemical substances registered under REACH.
  8. PubChem. National Library of Medicine; National Center for Biotechnology Information. Available at: https://pubchem.ncbi.nlm.nih.gov.
  9. OECD SIDS. Initial Assessment Report, 2001. – 82 р.
  10. GHS Classification Results (J-GHS). National Institute of Technology and Evaluation /NITE/. Japan.
  11. Database of the Federal Register of Potentially Hazardous Chemical and Biological Substances (in Russian).
  12. The OECD QSAR Toolbox. Available at: https://www.oecd.org/chemicalsafety/ risk-assessment/oecd-qsar-toolbox.htm.
  13. Р 1323565.1.027- 2019 «Guidelines for grouping similar chemicals into toxicologically relevant categories to fill data gaps in information on toxicity using the OECD QSAR Toolbox» (in Russian).
  14. o-Phthalic acid [88-99-3; phthalic acid], m-phthalic acid [121- 91-5; isophthalicacid], p-phthalic acid [100-21-0; terephthalic acid]. Deutsche Forschungsgemeinschaft. Available at: https://onlinelibrary.wiley.com/ doi/epdf/ 10.1002/ 3527600418. mb8899isme52

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Copyright (c) 2021 Khamidulina K.K., Radilov A.S., Dulov S.A., Zemlyanoy A.V., Beltyukov P.P., Vivulanets E.V., Kucherskoy S.A., Shishonok M.F., Tarasova E.V., Proskurina A.S., Egiazaryan A.R., Zamkova I.V., Dorofeeva E.V., Rinchindorzhieva E.A., Rabikova D.N., Shvykina S.A.



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