TOXICITY AND HAZARD OF NEUROPARALYTIC ACTION OF FIRE-RESISTANT TURBINE OILS BASED ON TRIARYL PHOSPHATES

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Abstract

The paper presents the results of assessing the toxicity and danger of the development of neuroparalytic effect of fire-resistant turbine oils «Turbomas», «T-94» and «T-95» based on triaryl phosphates. According to the toxicity parameters, the studied oils are low-toxic substances, exhibit weakly expressed cumulative properties, do not irritate the skin and mucous membranes, penetrate through intact skin, and increase the activity of microsomal enzymes, when injected into the stomach and abdominal cavity. The study of the neuroparalytic action of oils «Turbomas», «T-94» and «T-95» did not reveal the presence of clinical and morphological signs of disorders of the neuromuscular apparatus in animals, which makes it possible to exclude the possibility of neuroparalytic action in persons in contact with the studied oils.

About the authors

G. I. Sidorin

Institute of Toxicology of the Federal Medical Biological Agency

Author for correspondence.
Email: sidorin.g@mail.ru
192019, Saint Petersburg Russian Federation

L. V. Lukovnikova

Institute of Toxicology of the Federal Medical Biological Agency

Email: lukovnikova.l.v@toxicology.ru
192019, Saint Petersburg Russian Federation

L. I. Dyakova

Institute of Toxicology of the Federal Medical Biological Agency

Email: lukovnikova.l.v@toxicology.ru
192019, Saint Petersburg Russian Federation

G. V. Shestova

Institute of Toxicology of the Federal Medical Biological Agency

Email: gvshestova@mail.ru
192019, Saint Petersburg Russian Federation

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Copyright (c) 2020 Sidorin G.I., Lukovnikova L.V., Dyakova L.I., Shestova G.V.


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