Email this article TOXICITY OF DIOCTYLTEREPHTHALATE
- Authors: Mamonov R.A.1, Fedotova L.A.2,3, Pechnikova I.A.1, Potapchenko T.D.1
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Affiliations:
- Center for Strategic Planning and Management of Biomedical Health Risks, RF Ministry of Health.
- Center for Strategic Planning and Management of Biomedical Health Risks, RF Ministry of Health
- Russian Medical Academy of Continuous Professional Education, RF Ministry of Health.
- Issue: No 6 (2018)
- Pages: 47-49
- Section: New information on toxicity and hazard of chemical and biological substances
- Published: 28.12.2018
- URL: https://rjsvd.com/0869-7922/article/view/641154
- DOI: https://doi.org/10.36946/0869-7922-2018-6-47-49
- ID: 641154
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Abstract
Dioctylterephthalate is a general-purpose plasticizer, has low toxicity, and does not irritate the mucous membranes of the eye and the skin; the maximum nonlethal dose (DL0) for dioctylterephthalate after intragastric administration is set at 10,000 mg/kg. Indicative safe exposure level for dioctylterephthalate in ambient air in urban and rural settlements is recommended at 0.5 mg/m3. Substance has low acute toxicity; the maximum inactive dose is set at 4 mg/kg. The substance has low solubility in water (0.4 μg/l), does not affect the dynamics of biochemical oxygen consumption. Threshold concentration in water on organoleptic characteristic is set at 0.25 mg/l as for low hazard substances.
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About the authors
R. A. Mamonov
Center for Strategic Planning and Management of Biomedical Health Risks, RF Ministry of Health.
Author for correspondence.
Email: fake@neicon.ru
119121, Moscow. Russian Federation
L. A. Fedotova
Center for Strategic Planning and Management of Biomedical Health Risks, RF Ministry of Health; Russian Medical Academy of Continuous Professional Education, RF Ministry of Health.
Email: fake@neicon.ru
119121, Moscow.
125993, Moscow.
Russian FederationI. A. Pechnikova
Center for Strategic Planning and Management of Biomedical Health Risks, RF Ministry of Health.
Email: fake@neicon.ru
119121, Moscow. Russian Federation
T. D. Potapchenko
Center for Strategic Planning and Management of Biomedical Health Risks, RF Ministry of Health.
Email: fake@neicon.ru
119121, Moscow. Russian Federation
References
- Temporary methodical instructions on justification of maximum permissible concentrations (MPC) of pollutants in atmospheric air of inhabited places, VMU No. 4681-88. (n Russian)
- Justification of hygienic standards of chemicals in water of water objects of economicdrinking and cultural-household water use: Methodical instructions. MU 2.1.5.720-8. - M.: Federal center of Gossanepidnadzor of the Ministry of Health of the Russian Federation, 1999. (n Russian)
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