Synthesis of substituted cyclohexenones by reaction of chalcones with acetoacetic acid amides

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Abstract

New 4-aryl-2-oxo-6-phenyl-3-cyclohexene-1-carboxamides were obtained by the reaction of N -substituted acetoacetic acid amides with benzalacetophenone and 4-methoxybenzalacetophenone in alcohol in the presence of potassium hydroxide. Structure of the prepared compounds was proved using IR, 1H and 13C NMR spectroscopy, mass spectrometry and X-rays analysis data.

About the authors

N. V. Nosova

Perm State Pharmaceutical Academy

A. A. Sokolov

Perm State Pharmaceutical Academy

V. L. Gein

Perm State Pharmaceutical Academy

Email: geinvl48@mail.ru

M. V. Dmitriev

Perm State National Research University

I. G. Mokrushin

Perm State National Research University

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