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Effect of Pulsed Electron Beam Treatment on the Release Profile of Chloramphenicol from Polylactic Acid–Based Polymeric Scaffolds
- Authors: Volokhova A.A.1,2, Ponomarev D.V.3, Kurzina I.A.1, Tverdokhlebov S.I.2
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Affiliations:
- National Research Tomsk State University
- Weinberg Research Center, National Research Tomsk Polytechnic University
- Research and Production Laboratory of Pulse-Beam, Electric Discharge, and Plasma Technologies, National Research Tomsk Polytechnic University
- Issue: Vol 57, No 3 (2023)
- Pages: 201-205
- Section: RADIATION CHEMISTRY
- URL: https://rjsvd.com/0023-1193/article/view/661505
- DOI: https://doi.org/10.31857/S0023119323030178
- EDN: https://elibrary.ru/KIPECN
- ID: 661505
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Abstract
The paper presents the results of testing the properties of antibacterial nonwoven fibrous materials based on polylactic acid with incorporated chloramphenicol. It has been shown that exposure to a pulsed electron beam increased the rate of release of chloramphenicol into a phosphate-buffered saline medium. In this case, the amount of the substance released from treated samples was reliably greater than that with untreated samples during the five days of the experiment
About the authors
A. A. Volokhova
National Research Tomsk State University; Weinberg Research Center, National Research Tomsk Polytechnic University
Email: rapollinariya@gmail.com
Tomsk, 634050 Russia; Tomsk, 634050 Russia
D. V. Ponomarev
Research and Production Laboratory of Pulse-Beam, Electric Discharge, and Plasma Technologies, National Research Tomsk Polytechnic University
Email: rapollinariya@gmail.com
Tomsk, 634050 Russia
I. A. Kurzina
National Research Tomsk State University
Email: rapollinariya@gmail.com
Tomsk, 634050 Russia
S. I. Tverdokhlebov
Weinberg Research Center, National Research Tomsk Polytechnic University
Author for correspondence.
Email: rapollinariya@gmail.com
Tomsk, 634050 Russia
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