Email this article 
Effect of Copper Ions on Quercetin Reactivity in Free Radical Reactions and Radioprotective Activity
- Authors: Lysenko A.G.1, Fenin A.A.1
-
Affiliations:
- Mendeleev University of Chemical Technology
- Issue: Vol 57, No 3 (2023)
- Pages: 198-200
- Section: RADIATION CHEMISTRY
- URL: https://rjsvd.com/0023-1193/article/view/661504
- DOI: https://doi.org/10.31857/S0023119323030087
- EDN: https://elibrary.ru/KDOJBR
- ID: 661504
Cite item
Open Access
Access granted
Subscription Access
Abstract
Steady state radiolysis showed a decrease in the reactivity of quercetin in free radical reactions with the 1-hydroxyethyl radical and the superoxide radical anion as a result of the formation of a complex with a copper ion. The negative effect of copper ions can be reduced via destroying the resulting complex by introducing chelating compounds, such as tartaric acid and EDTA. The nature of the change in reactivity corresponded to the change in the radioprotective activity of quercetin in relation to yeast cells.
About the authors
A. G. Lysenko
Mendeleev University of Chemical Technology
Email: fenin.a.a@muctr.ru
Moscow, 125480 Russia
A. A. Fenin
Mendeleev University of Chemical Technology
Author for correspondence.
Email: fenin.a.a@muctr.ru
Moscow, 125480 Russia
References
- Кудряшов Ю. Б. Радиационная биофизика (ионизирующие излучения) / Под ред. В.К. Мазурика, М.Ф. Ломанова. М.: ФИЗМАТЛИТ, 2004. 448 с.
- Zeng Y., Song J., Zhang M., Wang H., Zhang Y., Suo H.. // Antioxidants (Basel). 2020. V. 9(8). P. 732. PMID; PMCID: PMC7465758.https://doi.org/10.3390/antiox908073232796543
- Raman S.T., Ganeshan A.K., Chen C., Jin C., Li S.H., Chen H.J., Gui Z. // Pharmacogn Mag. 2016. V. 12(46). P. 128–33. PMID; PMCID: PMC4809167.https://doi.org/10.4103/0973-1296.17791027076749
- Terao J. // The J. Medical Investigation: JMI. 1999. V. 46(3–4). P. 159–168. PMID: 10687310
- Procházková D., Boušová I., Wilhelmová N. // Fitoterapia. 2011. T. 82. № 4. C. 513.
- Lekka C.E. et al. // The J. Physical Chemistry B. 2009. T. 113. № 18. C. 6478.
- Костюк В.А. Биорадикалы и биоантиоксиданты / В.А. Костюк, А.И. Потапович. Минск. 2004. С. 10–16; С. 82–98.
- Jomová K., Hudecova L., Lauro P., Simunkova M., Alwasel S.H., Alhazza I.M., Valko M. // Molecules. 2019. V. 24(23). P. 4335. PMID; PMCID: PMC6930463.https://doi.org/10.3390/molecules2423433531783535
- Žuvela P., David J., Yang X., Huang D., Wong M.W. // Int. J. Mol. Sci. 2019. V. 20(9). P. 2328. PMID; PMCID: PMC6539043.https://doi.org/10.3390/ijms2009232831083440
- Simunkova M., Barbierikova Z., Jomova K., Hudecova L., Lauro P., Alwasel S.H., Alhazza I., Rhodes C.J., Valko M. // Int. J. Mol. Sci. 2021. V. 22(4). P. 1619. PMID; PM-CID: PMC7915082.https://doi.org/10.3390/ijms2204161933562744
- Суворова А.А., Фенин А.А. // Радиационная биология. Радиоэкология. 2010. Т. 50. № 2. С. 180.
Supplementary files
