The state of the main vessels in workers of heavy industries

Cover Page

Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access

Abstract

Introduction. The prevalence of atherosclerosis in the Russian Federation has been poorly studied due to the large number of population groups. The assessment of the atherosclerosis rate is controversial because of different approaches and combinations of the examined vascular beds, while asymptomatic atherosclerosis is increasingly being detected due to the lack of proper attention of clinicians to patients of the middle group of cardiovascular fatal risk.

Materials and methods. Three hundred eighty five long-term labour experience 40 to 55 years workers of the main occupations of the coal and aluminum industry were examined. Using the SCORE scale, 78 miners and 79 metallurgists with average risk from 2 to 4% were identified from the total sample. All cases underwent ultrasound examination of the main arteries. The risk factors included in the fatal risk SCORE scale had been studied.

Results. A comparison of the atherosclerotic process of the main arteries in the studied groups revealed a high occurence of multifocal atherosclerosis, to a greater extent in miners – 80.3%, which is significantly less in comparison with aluminum production workers – 54.2%, p=0.020. The share of persons with a lesion of one vascular bed in the form of stenosis among miners significantly exceeded that of metallurgists: 68.0% and 50.6%, p=0.027. The same trend was observed in the brachiocephalic arteries (42.3 vs. 21.5%, p=0.005) and the main arteries of the lower extremities (55.1 vs. 34.2%, p=0.008), respectively. There were no significant differences in the commonly accepted risk factors for atherosclerosis between the groups.

Limitations. The study is limited to the number of patients with the signs corresponding to the middle fatal risk group on the SCORE scale.

Conclusion. The frequency of atherosclerosis among workers in the main occupations in the coal and aluminum industry, who have a moderate fatal risk, turned out to be extremely high, and to a greater extent in miners, which requires urgent preventive measures and medical supervision. Commonly accepted factors of moderate risk groups according to the SCORE scale of the studied occupational cohort were not leading in the development of atherosclerosis.

Compliance with ethical standards. All subjects signed an informed consent to participate in the study, the protocol of which corresponded to the requirements of the Bioethical Committee of the Research Institute for Complex Problems of Hygiene and Occupational Diseases, executed in accordance with the Declaration of Helsinki of the World Medical Association “Ethical Principles for Medical Research Involving Human Subjects” as amended 2013 and the “Rules of Proper Clinical Practice” approved by Order of the Ministry of Health of the Russian Federation dated April 1, 2016 N 200n.

Contribution:
Korotenko O.Yu. – collection of material, writing a text;
Filimonov E.S. – the concept and design of the study, statistical processing, writing a text;
Mikhailova N.N. – editing;
Ulanova E.V. – collection of material.
All authors are responsible for the integrity of all parts of the manuscript and approval of the manuscript final version.

Conflict of interest. The authors declare no conflict of interest.

Acknowledgement. The study had no sponsorship.

Received: April 15, 2024 / Accepted: June 19, 2024 / Published: July 31, 2024

About the authors

Olga Yu. Korotenko

Research Institute for Complex Problems of Hygiene and Occupational Diseases

Author for correspondence.
Email: olgakorotenko@yandex.ru
ORCID iD: 0000-0001-7158-4988

MD, PhD, Deputy Director on Science, Research Institute for Complex Problems of Hygiene and Occupational Diseases, Novokuznetsk, 654041, Russian Federation

e-mail: olgakorotenko@yandex.ru

Russian Federation

Egor S. Filimonov

Research Institute for Complex Problems of Hygiene and Occupational Diseases

Email: 171fes@gmail.com
ORCID iD: 0000-0002-2204-1407

MD, PhD, head of the scientific and advisory department of the Clinic of the Research Institute for Complex Problems of Hygiene and Occupational Diseases, Novokuznetsk, 654041, Russian Federation

e-mail: 171fes@gmail.com

Russian Federation

Nadezhda N. Mikhailova

Research Institute for Complex Problems of Hygiene and Occupational Diseases

Email: napmih@mail.ru
ORCID iD: 0000-0002-1127-6980

MD, PhD, DSci., chief researcher, Lab. of molecular genetics and experimental research of the Research Institute for Complex Problems of Hygiene and Occupational Diseases, Novokuznetsk, 654041, Russian Federation

e-mail: napmih@mail.ru

Russian Federation

Evgeniya V. Ulanova

Research Institute for Complex Problems of Hygiene and Occupational Diseases

Email: sledui_mechte@mail.ru
ORCID iD: 0000-0003-2657-3862

MD, PhD, senior researcher, Lab. of pathomorpholory of occupation-related diseases, Research Institute for Complex Problems of Hygiene and Occupational Diseases, Novokuznetsk, 654041, Russian Federation

e-mail: sledui_mechte@mail.ru

Russian Federation

References

  1. Potemkina R.A., Myl’nikova L.A., Kamynina N.N., Pivovarova O.A. Prevention of noncommunicable diseases: from risk factors to the national programs. Zdravookhranenie Rossiiskoi Federatsii. 2021; 65(5): 440–6. https://doi.org/10.47470/0044-197X-2021-65-5-440-446 https://elibrary.ru/tcczas (in Russian)
  2. Serdyukov D.Yu., Gordienko A.V., Grigorev S.G., Mavrenkov E.M., Ignatov O.G. Cardiovascular risk and subclinical atherosclerosis signs in a military contingent based in the Arctic. Vestnik Rossiiskoi voenno-meditsinskoi akademii. 2017; (1): 43–7. https://elibrary.ru/yjmgmb (in Russian)
  3. European Guidelines on Cardiovascular Diseases Prevention in Clinical Practice. Rossiiskii kardiologicheskii zhurnal. 2017; 22(6): 7–85. https://elibrary.ru/yttvav (in Russian)
  4. Tregubov A.V., Tregubova A.A., Alekseeva I.V., Savchuk K.I., Urazgildeeva S.A. Comparison of the results of cardiovascular risk assessment using the SCORE and SCORE2 scales. Ateroskleroz i dislipidemii. 2022; (3): 41–7. https://doi.org/10.34687/2219-8202.JAD.2022.03.0005 https://elibrary.ru/nmhihc (in Russian)
  5. Fernández-Alvira J.M., Fuster V., Pocock S., Sanz J., Fernández-Friera L., Laclaustra M., et al. Predicting Subclinical Atherosclerosis in Low-Risk Individuals: Ideal Cardiovascular Health Score and Fuster-BEWAT Score. J. Am. Coll. Cardiol. 2017; 70(20): 2463–73. https://doi.org/10.1016/j.jacc.2017.09.032
  6. Wang H.Y., Dou K.F., Sun Y.X. Fuster-BEWAT score versus cardiovascular health score to predict subclinical target organ damage: Insights from a large-scale Asian population. Eur. J. Prev. Cardiol. 2020; 27(19): 2292–5. https://doi.org/10.1177/2047487319891781
  7. Shal’nova S.A., Drapkina O.M. Contribution of the ESSE-RF study to preventive healthcare in Russia. Kardiovaskulyarnaya terapiya i profilaktika. 2020; 19(3): 209–15. https://doi.org/10.15829/1728-8800-2020-2602 https://elibrary.ru/fjkwqq (in Russian)
  8. Agafonov P.E. Prospects for the Coal Industry in the Russian Federation. Nauka i biznes: puti razvitiya. 2023; (5): 88–93. https://elibrary.ru/bjecon (in Russian)
  9. Bukhtiyarov I.V., Chebotarev A.G., Kur’erov N.N., Sokur O.V. Topical issues of improving working conditions and preserving the health of workers of mining enterprises. Meditsina truda i promyshlennaya ekologiya. 2019; 59(7): 424–9. https://doi.org/10.31089/1026-9428-2019-59-7-424-429 https://elibrary.ru/ejxzmd (in Russian)
  10. Chebotarev A.G., Duryagin I.N. Improvement of working conditions is important task to preserve health of employees of aluminum plants. Metallurg. 2017; (10): 9–12. https://elibrary.ru/zqqdrr (in Russian)
  11. Ustinova O.Yu., Vlasova E.M., Nosov A.E., Kostarev V.G., Lebedeva T.M. Assessment of cardiovascular pathology risk in miners employed at deep chrome mines. Analiz riska zdorov’yu. 2018; (3): 94–103. https://doi.org/10.21668/health.risk/2018.3.10.eng https://elibrary.ru/dhohpq
  12. Meshchakova N.M., Shayakhmetov S.F., Rukavishnikov V.S., Merinov A.V. Assessment of occupational health risk for employees of the main occupations of aluminum production. Gigiena i Sanitaria (Hygiene and Sanitation, Russian journal). 2020; 99(10): 1106–11. https://doi.org/10.47470/0016-9900-2020-99-10-1106-1111 https://elibrary.ru/bokzth (in Russian)
  13. Korotenko O.Yu., Filimonov E.S., Panev N.I., Ulanova E.V. Comparative assessment of the state of main arteries in workers of the pivotal occupations in the coal and aluminum industries. Gigiena i Sanitaria (Hygiene and Sanitation, Russian journal). 2023; 102(7): 658–63. https://doi.org/10.47470/0016-9900-2023-102-7-658-663 https://elibrary.ru/qcykrx (in Russian)
  14. Kulikov V.P. Ultrasound Diagnosis of Vascular Diseases [Ul’trazvukovaya diagnostika sosudistykh zabolevanii]. Moscow: STROM; 2011. https://elibrary.ru/rsxofh (in Russian)
  15. Boitsov S.A., Pogosova N.V., Bubnova M.G., Drapkina O.M., Gavrilova N.E., Eganyan R.A., et al. Cardiovascular prevention 2017. National guidelines. Rossiiskii kardiologicheskii zhurnal. 2018; 23(6): 7–122. https://doi.org/10.15829/1560-4071-2018-6-7-122 https://elibrary.ru/xslttf (in Russian)
  16. Ershova A.I., Balakhonova T.V., Meshkov A. N., Kutsenko V.A., Yarovaya E.B., Shalnova S.A., et al. Prevalence of carotid and femoral artery atherosclerosis among the Ivanovo Oblast population: data from the ATEROGEN-Ivanovo study. Kardiovaskulyarnaya terapiya i profilaktika. 2021; 20(5): 262–70. https://doi.org/10.15829/1728-8800-2021-2994 https://elibrary.ru/bfatef (in Russian)
  17. Thorsson B., Eiriksdottir G., Sigurdsson S., Gudmundsson E.F., Bots M.L., Aspelund T., et al. Population distribution of traditional and the emerging cardiovascular risk factors carotid plaque and IMT: the REFINE-Reykjavik study with comparison with the Tromsø study. BMJ Open. 2018; 8(5): e019385. https://doi.org/10.1136/bmjopen-2017-019385
  18. Bugaeva M.S., Gorokhova L.G., Bondarev O.I., Mikhailova N.N. Influence of coal-rock dust on the risk of developing morphological disorders of the cardiovascular system. Meditsina truda i promyshlennaya ekologiya. 2020; 60(6): 415–20. https://doi.org/10.31089/1026-9428-2020-60-6-415-420 https://elibrary.ru/wrhpcj (in Russian)
  19. Yadykina T.K., Korotenko O.Yu., Panev N.I., Semenova E.A., Zhukova A.G., Mikhailova N.N. Clinical and experimental studies of cardiovascular disorders in the conditions of fluoride intoxication of the body. Meditsina truda i promyshlennaya ekologiya. 2020; 60(6): 375–80. https://doi.org/10.31089/1026-9428-2020-60-6-375-380 https://elibrary.ru/gnbtvp (in Russian)
  20. Sumin A.N., Gaifulin R.A., Bezdenezhnykh A.V., Moskin M.G., Korok E.V., Karpovich A.V., et al. Prevalence of multifocal atherosclerosis in different age groups. Kardiologiya. 2012; 52(6): 28–34. https://elibrary.ru/puaabn (in Russian)
  21. Lodygina K.V. Prevalence of subclinical atherosclerosis in young people. Sinergiya nauk. 2018; (22): 1172–7. https://elibrary.ru/ywzvkp (in Russian)
  22. Khovaeva Ya.B., Shavrin A.P., Korovin A.L., Moiseenko N.P. The role of smoking in vascular wall pathology. APRIORI. Seriya: Estestvennye i tekhnicheskie nauki. 2016; (6): 32. https://elibrary.ru/zaxdiz (in Russian)
  23. Safaryan A.S., Lishuta A.S., Nebieridze D.V. Uric Acid as a Risk Factor for Cardiovascular Diseases. Ratsional’naya farmakoterapiya v kardiologii. 2022; 18(4): 473–9. https://doi.org/10.20996/1819-6446-2022-08-15 https://elibrary.ru/mfcpil (in Russian)
  24. Liu N., Xu H., Sun Q., Yu X., Chen W., Wei H., et al. The Role of Oxidative Stress in Hyperuricemia and Xanthine Oxidoreductase (XOR) Inhibitors. Oxid. Med. Cell Longev. 2021; 2021: 1470380. https://doi.org/10.1155/2021/1470380
  25. Bershtein L.L., Golovina A.E., Katamadze N.O., Bondareva E.V., Saiganov S.A. Evaluating of the accurasy of cardiovascular events predicting using SCORE scale and ultrasound visualization of atherosclerotic plaque in patients of multi-disciplinary hospital in Saint-Petersburg: medium-term monitoring data. Rossiiskii kardiologicheskii zhurnal. 2019; 24(5): 20–5. https://doi.org/10.15829/1560-4071-2019-5-20-25 https://elibrary.ru/qmidkf (in Russian)

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2024 Korotenko O.Y., Filimonov E.S., Mikhailova N.N., Ulanova E.V.



СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 37884 от 02.10.2009.