Treatment of endotoxinemia syndrome in patients with atopic dermatitis

The role of endotoxin in pathogenesis of atopic dermatitis (AD) is discussed. A total of 81 patients with AD were examined (68 men and 13 women from 16 to 53 years old). In 60% of patients disorders of gastro-intestinal tract were diagnosed, in 90% of subjects disbalance of gastrointestinal microflora was detected. In all patients mean level of endotoxin (lipopolyssacharide) in blood was above normal. A pathogenetic method of AD treatment is suggested including enterosorbents, probiotics, and hepatoprotectors.

atopic dermatitis, endotoxin, endotoxin aggression, antiendotoxin therapy