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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Skin and Venereal Diseases</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Skin and Venereal Diseases</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский журнал кожных и венерических болезней</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1560-9588</issn><issn publication-format="electronic">2412-9097</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">63949</article-id><article-id pub-id-type="doi">10.17816/dv63949</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DERMATOLOGY</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДЕРМАТОЛОГИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Pustular psoriasis and arthropathy in a patient with HIV infection. Clinical case</article-title><trans-title-group xml:lang="ru"><trans-title>Пустулёзный псориаз и артропатия у больного ВИЧ-инфекцией. Клинический случай</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2674-1096</contrib-id><contrib-id contrib-id-type="spin">3577-7335</contrib-id><name-alternatives><name xml:lang="en"><surname>Dubensky</surname><given-names>Valery V.</given-names></name><name xml:lang="ru"><surname>Дубенский</surname><given-names>Валерий Викторович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>доктор медицинских наук, профессор кафедры дерматовенерологии с курсом косметологии</p></bio><email>valerydubensky@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2805-6749</contrib-id><contrib-id contrib-id-type="spin">5831-5824</contrib-id><name-alternatives><name xml:lang="en"><surname>Nekrasova</surname><given-names>Elizaveta G.</given-names></name><name xml:lang="ru"><surname>Некрасова</surname><given-names>Елизавета Георгиевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.), Associate Professor</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук, доцент кафедры дерматовенерологии с курсом косметологии</p></bio><email>nekrasova-7@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5583-928X</contrib-id><contrib-id contrib-id-type="spin">6044-8507</contrib-id><name-alternatives><name xml:lang="en"><surname>Dubensky</surname><given-names>Vladislav V.</given-names></name><name xml:lang="ru"><surname>Дубенский</surname><given-names>Владислав Валерьевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD, Professor of the Department of Dermatovenerology with the course of Cosmetology</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук, профессор кафедры дерматовенерологии с курсом косметологии</p></bio><email>dubensky.vladislav@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8281-3619</contrib-id><contrib-id contrib-id-type="spin">8080-0721</contrib-id><name-alternatives><name xml:lang="en"><surname>Alexandrova</surname><given-names>Olga A.</given-names></name><name xml:lang="ru"><surname>Александрова</surname><given-names>Ольга Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Assistant at the Department of Dermatovenereology with a course of cosmetology</p></bio><bio xml:lang="ru"><p>ассистент кафедры дерматовенерологии с курсом косметологии</p></bio><email>olyaxandrova@gmail.com</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5326-4876</contrib-id><contrib-id contrib-id-type="spin">3332-8424</contrib-id><name-alternatives><name xml:lang="en"><surname>Muraveva</surname><given-names>Ekaterina S.</given-names></name><name xml:lang="ru"><surname>Муравьева</surname><given-names>Екатерина Сергеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Assistant at the Department of Dermatovenereology with a course of cosmetology</p></bio><bio xml:lang="ru"><p>ассистент кафедры дерматовенерологии с курсом косметологии</p></bio><email>katerisha87@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Tver State Medical University</institution></aff><aff><institution xml:lang="ru">Тверской государственный медицинский университет</institution></aff><aff><institution xml:lang="zh"></institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Tver State Medical University</institution></aff><aff><institution xml:lang="ru">Тверской государственный медицинский университет</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2021-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2021</year></pub-date><volume>24</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>151</fpage><lpage>160</lpage><history><date date-type="received" iso-8601-date="2021-03-22"><day>22</day><month>03</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-05-20"><day>20</day><month>05</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, ООО "Эко-Вектор"</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2025-08-01"/></permissions><self-uri xlink:href="https://rjsvd.com/1560-9588/article/view/63949">https://rjsvd.com/1560-9588/article/view/63949</self-uri><abstract xml:lang="en"><p>The article presents a clinical case of pustular psoriasis and arthropathy in a patient with HIV infection. The diagnosis of psoriasis was confirmed by morphological examination. Signs of arthropathy were confirmed by X-Ray: presence of oligoarthritis of the distal interphalangeal joints of the fingers and feet was seen. Dactylitis severity ― 2–3 points, the Ritchie index ― 2, DLQI ― 28. The clinical course of psoriasis and its treatment in HIV-infected patients was considered after taking into account the data from literature and the patients current condition and observation. The above observation of a combination of several clinical forms of psoriasis (vulgar, pustular and arthropathy) in patients with HIV infection is an illustration of the features of the course and comorbidity of chronic dermatosis and AIDS, due to the influence of the infectious process, immunosuppression and ART. The development of pustular form and arthropathy creates the additional challenge of prescribing basic systemic treatment for severe and complicated psoriasis in an HIV-infected patient due to the presence of contraindications due to comorbidity. The glucocorticosteriod selected by the committee was effective on the skin and joint pathological processes, without having any negative impact on the course and treatment of the HIV infection. Such cases require further study and development of methods for the treatment of patients with comorbidity and their inclusion in an additional section in the clinical recommendations for the diagnosis and treatment of psoriasis.</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлен клинический случай сочетания нескольких форм псориаза (вульгарного, пустулёзного) и артропатии у больной ВИЧ-инфекцией. Диагноз псориаза подтверждён морфологическим исследованием. Признаки артропатии установлены при рентгенографии: выявлено наличие олигоартрита дистальных межфаланговых суставов пальцев кистей и стоп. Степень выраженности дактилита ― 2–3 балла, индекс Ричи ― 2, дерматологический индекс качества жизни ― 28. Обсуждается необходимость междисциплинарного подхода к лечению данной больной с учётом коморбидного состояния. Рассматриваются варианты клинического течения псориаза и особенности его лечения у ВИЧ-инфицированных больных с учётом данных литературы и собственного наблюдения. Представленный случай является иллюстрацией особенностей течения и коморбидности хронического дерматоза и СПИДа, обусловленного влиянием инфекционного процесса, иммуносупрессии и антиретровирусной терапии. Развитие пустулёзной формы и артропатии создаёт дополнительную проблему назначения базового системного лечения при тяжёлом и осложнённом псориазе у ВИЧ-инфицированного больного из-за наличия противопоказаний, обусловленных коморбидностью. Комиссионно выбранный глюкокортикостероид оказался эффективным в отношении кожного и суставного процесса, не оказав негативного воздействия на течение и терапию ВИЧ-инфекции. Терапевтические методики для категории пациентов с коморбидностью требуют дальнейших разработок с последующим их включением в дополнительный раздел клинических рекомендаций по диагностике и лечению псориаза.</p></trans-abstract><kwd-group xml:lang="en"><kwd>psoriasis</kwd><kwd>HIV infection</kwd><kwd>pustular psoriasis</kwd><kwd>psoriatic arthropathy</kwd><kwd>comorbidity</kwd><kwd>clinical features</kwd><kwd>immunosuppression</kwd><kwd>treatment</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>псориаз</kwd><kwd>ВИЧ-инфекция</kwd><kwd>пустулёзный псориаз</kwd><kwd>псориатическая артропатия</kwd><kwd>коморбидность</kwd><kwd>клинические особенности</kwd><kwd>иммуносупрессия</kwd><kwd>лечение</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Galegov GA, Lviv DK. HIV infection: clinic, diagnosis, treatment. Epidemiology of infectious diseases. 2003;(3):62–64. 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