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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Skin and Venereal Diseases</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Skin and Venereal Diseases</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский журнал кожных и венерических болезней</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1560-9588</issn><issn publication-format="electronic">2412-9097</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">636703</article-id><article-id pub-id-type="doi">10.17816/dv636703</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DERMATOLOGY</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДЕРМАТОЛОГИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Laser therapies for the treatment of necrobiosis lipoidica: literature review and own experience</article-title><trans-title-group xml:lang="ru"><trans-title>Лазерные методы лечения липоидного некробиоза: обзор литературы и собственный опыт</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5826-5018</contrib-id><contrib-id contrib-id-type="spin">4437-3800</contrib-id><name-alternatives><name xml:lang="en"><surname>Morozova</surname><given-names>Elena A.</given-names></name><name xml:lang="ru"><surname>Морозова</surname><given-names>Елена Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>doc.elene@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5800-4800</contrib-id><contrib-id contrib-id-type="spin">8013-3256</contrib-id><name-alternatives><name xml:lang="en"><surname>Teplyuk</surname><given-names>Natalia P.</given-names></name><name xml:lang="ru"><surname>Теплюк</surname><given-names>Наталия Павловна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор</p></bio><email>Teplyukn@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5471-6130</contrib-id><contrib-id contrib-id-type="spin">3505-7408</contrib-id><name-alternatives><name xml:lang="en"><surname>Rogozina</surname><given-names>Varvara A.</given-names></name><name xml:lang="ru"><surname>Рогозина</surname><given-names>Варвара Андреевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>varvara.rgzn@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution></aff><aff><institution xml:lang="ru">Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет)</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2025-03-30" publication-format="electronic"><day>30</day><month>03</month><year>2025</year></pub-date><pub-date date-type="pub" iso-8601-date="2025-02-06" publication-format="electronic"><day>06</day><month>02</month><year>2025</year></pub-date><volume>28</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>53</fpage><lpage>62</lpage><history><date date-type="received" iso-8601-date="2024-10-04"><day>04</day><month>10</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-10-26"><day>26</day><month>10</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Эко-Вектор</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2028-01-01"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0/</ali:license_ref></license></permissions><self-uri xlink:href="https://rjsvd.com/1560-9588/article/view/636703">https://rjsvd.com/1560-9588/article/view/636703</self-uri><abstract xml:lang="en"><p>Necrobiosis lipoidica is a rare, chronic skin disease of vascular-exchange character from the group of localised skin lipoidosis, characterised by collagen degeneration. The main methods of treatment of this dermatosis do not always have a positive effect and do not lead to long-term remission. In this regard, in recent years, new methods of the treatment for necrobiosis lipoidica have appeared, in particular laser treatment. The aim of this study is to investigate the efficacy and safety of laser therapy for necrobiosis lipoidica, as well as to report on our own experience of using IPL therapy for necrobiosis lipoidica.</p> <p>A review of scientific publications on the topic over the past 5 years on platforms such as PubMed and Google Scholar was conducted. Laser treatments used in the selected studies included CO<sub>2</sub> laser, dye laser and broadband intense pulsed light radiation (IPL therapy). Publications that used combined treatments were excluded.</p> <p>The description of our own experience of using intense pulsed light for the treatment of necrobiosis lipoidica in four patients with a positive effect in the form of reduction of telangiectasias, discoloration and flattening of the peripheral boundaries is presented. In connection with the increasing interest to laser methods of therapy of various dermatoses, we consider it important to study and apply them in the treatment of necrobiosis lipoidica, which may help to develop a new approach to the treatment of necrobiosis lipoidica.</p></abstract><trans-abstract xml:lang="ru"><p>Липоидный некробиоз ― редкое хроническое заболевание кожи сосудисто-обменного характера из группы локализованных липоидозов кожи, характеризующееся дегенерацией коллагена. Основные методы лечения данного дерматоза не всегда оказывают выраженный положительный эффект и не приводят к длительной ремиссии, в связи с чем в последние годы появились новые методы лечения липоидного некробиоза, в частности лазерный.</p> <p>В статье приводятся данные научных публикаций по эффективности и безопасности лазерной терапии липоидного некробиоза, размещённых на платформах PubMed и Google Scholar за последние 5 лет. Лазерные методы лечения, использованные в выбранных исследованиях, включали СО<sub>2</sub>-лазер, лазер на красителях и широкополосное интенсивное импульсное световое излучение (IPL-терапия). Публикации, в которых использовались комбинированные методы лечения, исключались.</p> <p>Представлено описание собственного опыта применения широкополосного интенсивного импульсного светового излучения для лечения липоидного некробиоза у четырёх пациентов с выраженным положительным эффектом в виде уменьшения количества телеангиэктазий, снижения интенсивности окраски и уплощения периферического валика.</p> <p>В связи с возросшим интересом к лазерным методам терапии дерматозов различного генеза считаем важным изучение и применение технологий электромагнитного излучения оптического диапазона в лечении липоидного некробиоза, что, возможно, поможет разработать новый подход к терапии заболеваний группы кожных дислипидозов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>necrobiosis lipoidica</kwd><kwd>laser</kwd><kwd>laser therapy</kwd><kwd>intense pulsed light therapy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>липоидный некробиоз</kwd><kwd>лазер</kwd><kwd>лазерная терапия</kwd><kwd>IPL-терапия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Ionescu C, Petca A, Dumitrașcu MC, et al. 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