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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Skin and Venereal Diseases</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Skin and Venereal Diseases</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский журнал кожных и венерических болезней</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1560-9588</issn><issn publication-format="electronic">2412-9097</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">60488</article-id><article-id pub-id-type="doi">10.17816/dv60488</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CLINICAL PICTURE, DIAGNOSIS, AND THERAPY OF DERMATOSES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИКА, ДИАГНОСТИКА И ЛЕЧЕНИЕ ДЕРМАТОЗОВ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Dermatoscopic patterns in vitiligo</article-title><trans-title-group xml:lang="ru"><trans-title>Дерматоскопические паттерны витилиго</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7496-7551</contrib-id><name-alternatives><name xml:lang="en"><surname>Davletshina</surname><given-names>Alina Yu.</given-names></name><name xml:lang="ru"><surname>Давлетшина</surname><given-names>Алина Юрьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Graduate student of the department of skin and venereal diseases named after V.A. Rakhmanova</p></bio><bio xml:lang="ru"><p>Аспирант кафедры кожных и венерических болезней им. В.А. Рахманова</p></bio><email>davletshinalina@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Lomonosov</surname><given-names>Konstantin M.</given-names></name><name xml:lang="ru"><surname>Ломоносов</surname><given-names>Константин Михайлович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Doctor of Medical Sciences, Professor of the department of skin and venereal diseases named after V.A. Rakhmanova</p></bio><bio xml:lang="ru"><p>доктор медицинских наук, профессор кафедры кожных и венерических болезней им. В.А. Рахманова</p></bio><email>davletshinalina@gmail.com</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">The State Education Institution of Higher Professional Training The First Sechenov Moscow State Medical University under Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">Федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет)</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Skin and Veneral desease Department of I.M. Sechenov First Moscow State Medical University</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО Первый МГМУ им. И.М. Сеченова Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2020</year></pub-date><volume>23</volume><issue>6</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>381</fpage><lpage>387</lpage><history><date date-type="received" iso-8601-date="2021-02-10"><day>10</day><month>02</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-03-22"><day>22</day><month>03</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2020, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2020, ООО "Эко-Вектор"</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2025-08-01"/></permissions><self-uri xlink:href="https://rjsvd.com/1560-9588/article/view/60488">https://rjsvd.com/1560-9588/article/view/60488</self-uri><abstract xml:lang="en"><p><italic><bold>BACKGROUND: </bold>Vitiligo is a chronic disease characterized by the appearance of depigmented spots on various parts of the body. Bright white spots on the skin cause the psychosocial maladjustment of individuals with this condition. To date, modern medicine lacks effective methods for the objective and accessible diagnosis of this disease. However, research methods, such as dermatoscopy, can be useful in diagnosing vitiligo and determining its stage.</italic></p> <p><italic><bold>AIM: </bold>This study aimed to identify the main dermatoscopic patterns of vitiligo in association with the activity of the process.</italic></p> <p><italic><bold>MATERIALS AND METHODS:</bold> To participate in the study, 63 patients with diagnosed vitiligo were examined. Patients participating in the study were divided into three groups: 34 patients with progressive course, 11 with stable condition, and 18 at the stage of repigmentation. A dermatoscopic examination was performed using a Delta 20T dermatoscope. Statistical processing of research materials was carried out using the SPSS statistics software package.</italic></p> <p><italic><bold>RESULTS:</bold> The most significant changes were found in the perifollicular area. Progressive vitiligo was characterized by perifollicular pigmentation (91.2%), an altered pigment network (97.1%), blurred spot border (94.1%), and specific structures, such as star-like formations and a “comet tail.” The stable vitiligo was characterized by perifollicular depigmentation (81.8%) and a sharp border of the spots (72.7%). For the stage of repigmentation, marginal hyperpigmentation (100%), perifollicular depigmentation (72.2%), blurred spot border (77.8%), and “islets of pigmentation” (77.8%) were observed.</italic></p> <p><italic><bold>CONCLUSION:</bold> The diagnostic dermatoscopic patterns of vitiligo have been developed for the first time, and their value has been proven. Dermatoscopy is a promising non-invasive auxiliary method used to diagnose vitiligo and determine the stage of the disease.</italic></p></abstract><trans-abstract xml:lang="ru"><p><italic><bold>ОБОСНОВАНИЕ. </bold>Витилиго – хроническое заболевание, характеризуемое появлением депигментированных пятен на различных участках тела. Яркие белые пятна на коже становятся для человека причиной психосоциальной дезадаптации. Современная медицина на данный момент не имеет эффективных методов объективной и доступной диагностики данного заболевания, однако такой метод исследования, как дерматоскопия, может быть полезен при постановке диагноза витилиго и определения его стадии.</italic></p> <p><italic><bold>ЦЕЛЬ</bold> – выявление основных дерматоскопических паттернов витилиго и установление связи с активностью процесса.</italic></p> <p><italic><bold>МАТЕРИАЛ И МЕТОДЫ.</bold> Для участия в исследовании было обследовано 63 пациента с диагнозом витилиго. Пациенты, включённые в исследование, были разделены на три группы: 34 пациента с нестабильной стадией (прогрессирующее витилиго), 11 – со стабильной стадией (стабильное витилиго), 18 – в стадии репигментации. В рамках работы было произведено дерматоскопическое исследование с помощью дерматоскопа Delta 20T. Статистическую обработку материалов исследования осуществляли с помощью пакета программ SPSS Statistics.</italic></p> <p><italic><bold>РЕЗУЛЬТАТЫ. </bold>Наиболее значимые изменения проявляются в перифолликулярной области. Для прогрессирующего витилиго характерны перифолликулярная пигментация (91,2%), изменённая пигментная сеть (97,1%), размытые границы пятна (94,1%), а также специфические структуры – звёздчатые образования и «хвост кометы». Для стабильного процесса витилиго характерны перифолликулярная депигментация (81,8%) и резкие границы пятна (72,7%), для стадии репигментации – краевая гиперпигментация (100%), перифолликулярная депигментация (72,2%), размытые границы пятна (77,8%) и «островки пигментации» (77,8%).</italic></p> <p><italic><bold>ЗАКЛЮЧЕНИЕ.</bold> Благодаря проведённым исследованиям впервые были разработаны диагностические дерматоскопические паттерны витилиго, доказана их ценность. Дерматоскопия является перспективным вспомогательным неинвазивным методом, применяемым для диагностики витилиго и определения стадии заболевания.</italic></p></trans-abstract><kwd-group xml:lang="en"><kwd>vitiligo</kwd><kwd>dermatoscopy</kwd><kwd>diagnostics</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>витилиго</kwd><kwd>дерматоскопия</kwd><kwd>диагностика</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Krüger C, Schallreuter KU. 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