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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Skin and Venereal Diseases</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Skin and Venereal Diseases</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский журнал кожных и венерических болезней</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1560-9588</issn><issn publication-format="electronic">2412-9097</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">42931</article-id><article-id pub-id-type="doi">10.17816/dv42931</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">THE CASE OF PSORIATIC ERYTHRODERMA AND SEVERE COMORBID PSORIATIC ARTHRITIS</article-title><trans-title-group xml:lang="ru"><trans-title>CЛУЧАЙ ПСОРИАТИЧЕСКОЙ ЭРИТРОДЕРМИИ И ТЯЖЕЛОГО КОМОРБИДНОГО ПСОРИАТИЧЕСКОГО АРТРИТА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Olisova</surname><given-names>O. Yu</given-names></name><name xml:lang="ru"><surname>Олисова</surname><given-names>О. Ю</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kochergin</surname><given-names>N. G</given-names></name><name xml:lang="ru"><surname>Кочергин</surname><given-names>Н. Г</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Belousova</surname><given-names>T. A</given-names></name><name xml:lang="ru"><surname>Белоусова</surname><given-names>Т. А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nikuradze</surname><given-names>Victoria O.</given-names></name><name xml:lang="ru"><surname>Никурадзе</surname><given-names>Виктория Олеговна</given-names></name></name-alternatives><bio xml:lang="en"><p>postgraduate of the Department of skin and venereal diseases of I.M. Sechenov First Moscow State Medical University (Sechenov University). Moscow, 119435, Russian Federation</p></bio><bio xml:lang="ru"><p>аспирант кафедры кожных и венерических болезней ФГБОУ ВО Первый Московский государственный университет им. И.М. Сеченoва Минздрава России, 119435, г. Москва, Россия</p></bio><email>victorianikuradze@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gudova</surname><given-names>V. V</given-names></name><name xml:lang="ru"><surname>Гудова</surname><given-names>В. В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Department of skin and venereal diseases of I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution></aff><aff><institution xml:lang="ru">Первый Московский государственный медицинский университет им. И.М. Сеченова</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2019-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2019</year></pub-date><volume>22</volume><issue>1-2</issue><issue-title xml:lang="en">VOL 22, NO1-2 (2019)</issue-title><issue-title xml:lang="ru">ТОМ 22, №1-2 (2019)</issue-title><fpage>15</fpage><lpage>23</lpage><history><date date-type="received" iso-8601-date="2020-08-24"><day>24</day><month>08</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2019, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2019, ООО "Эко-Вектор"</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://rjsvd.com/1560-9588/article/view/42931">https://rjsvd.com/1560-9588/article/view/42931</self-uri><abstract xml:lang="en"><p>Early diagnosis of psoriatic arthritis (PsA) is necessary for timely treatment and prevention of the disease progression with destruction of the joints. In most patients, comorbid PsA develops many years after the debut of the skin process. Consequently, the main role in timely diagnosis of PsA is played by a dermatologist, who is able to identify its initial signs and refer the patient to a rheumatologist. Early initiation of systemic therapy with the use of modern biological agents for progressive psoriatic arthritis and severe psoriasis can prevent the development of irreversible disability.</p></abstract><trans-abstract xml:lang="ru"><p>Ранняя диагностика псориатического артрита (ПсА) необходима для своевременной терапии и предотвращения прогрессирования заболевания с разрушением суставов. У большинства больных коморбидный ПсА развивается спустя много лет со времени дебюта самого кожного процесса. Следовательно, основную роль в своевременной постановке диагноза ПсА играет дерматолог, способный выявить его начальные признаки и направить пациента к ревматологу. Раннее начало системной терапии с применением современных биологических препаратов при прогрессирующем ПсА и тяжёлом псориазе может предотвратить развитие необратимой инвалидизации.</p></trans-abstract><kwd-group xml:lang="en"><kwd>psoriasis</kwd><kwd>psoriatic arthritis</kwd><kwd>biological therapy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>псориаз</kwd><kwd>псориатический артрит</kwd><kwd>биологическая терапия</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Myers W. A., Gottlieb A. B., Mease P. Psoriasis and psoriatic arthritis: clinical features and disease mechanisms. Clin. Dermatol. 2006; 24(5): 438-47.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Landells I., MacCallum C., Khraishi M. The role of the dermatologist in identification and treatment of the early stages of psoriatic arthritis. 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