Russian Journal of Skin and Venereal DiseasesRussian Journal of Skin and Venereal DiseasesРоссийский журнал кожных и венерических болезней1560-95882412-9097Eco-Vector3678810.17816/dv36788ArticlesСтатьиReview ArticleGENETIC ASPECTS OF VITILIGOГенетические аспекты витилиго (обзор литературы)SimonovaN. IСимоноваН. И

аспирант

LomonosovK. MЛомоносовК. М.

д-р мед. наук, проф.

lamdinic@yandex.ruBabeshkoO. AБабешкоО. А

врач

ГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздрава России15102012155NO5 (2012)№5 (2012)565921072020Copyright ©; 2012, Eco-VectorCopyright ©; 2012, ООО "Эко-Вектор"2012Eco-VectorООО "Эко-Вектор"https://rjsvd.com/1560-9588/article/view/36788

Modern data on the genetic aspects ofvitiligo epidemiology are presented. Vitiligo is an extensive genetically programmed autoimmune disease. Due to modern potentialities of clinical genetics, international studies have been carried out, aimed at detection of the genes involved in the formation of liability to this abnormality. The studies have been focused on the gene expression, associations of candidate gene alleles, and analysis of gene coupling in the genome in order to detect the new genes.

Представлены современные научные данные по генетическим аспектам эпидемиологии витилиго. Учитывая, что витилиго — широкое генетически запрограммированное аутоиммунное заболевание, а также современные возможности клинической генетики, авторы приводят международные данные выявления генов, участвующих в склонности к развитию этой патологии. Исследования включали экспрессию генов, исследования ассоциации аллелей генов-кандидатов, а также анализ сцепления генов в пределах генома с целью выявления новых генов.

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