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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Skin and Venereal Diseases</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Skin and Venereal Diseases</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский журнал кожных и венерических болезней</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1560-9588</issn><issn publication-format="electronic">2412-9097</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">36751</article-id><article-id pub-id-type="doi">10.17816/dv36751</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">THE ROLE OF LL-37 ANTIBACTERIAL PEPTIDE IN THE PATHOGENESIS OF PSORIASIS</article-title><trans-title-group xml:lang="ru"><trans-title>Роль антимикробного пептида LL-37 в патогенезе псориаза</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pinegin</surname><given-names>B. V</given-names></name><name xml:lang="ru"><surname>Пинегин</surname><given-names>Б. В.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, проф.</p></bio><email>bvpinegin@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ФГБУ Государственный научный центр Институт иммунологии ФМБА России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2012-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2012</year></pub-date><volume>15</volume><issue>5</issue><issue-title xml:lang="en">NO5 (2012)</issue-title><issue-title xml:lang="ru">№5 (2012)</issue-title><fpage>32</fpage><lpage>37</lpage><history><date date-type="received" iso-8601-date="2020-07-21"><day>21</day><month>07</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, ООО "Эко-Вектор"</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://rjsvd.com/1560-9588/article/view/36751">https://rjsvd.com/1560-9588/article/view/36751</self-uri><abstract xml:lang="en"><p>Published data on the role of LL-37 antibacterial peptide in initiation and inhibition of psoriatic inflammation are reviewed and probable approaches to its therapeutic use are discussed.</p></abstract><trans-abstract xml:lang="ru"><p>Представлен анализ данных литературы о роли антимикробного пептида LL-37 в инициации и ингибиции псориатического воспаления. Рассмотрены возможные пути его терапевтического применения.</p></trans-abstract><kwd-group xml:lang="en"><kwd>psoriasis</kwd><kwd>immune system cells</kwd><kwd>cytokines</kwd><kwd>LL-37 peptide</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>псориаз</kwd><kwd>клетки иммунной системы</kwd><kwd>цитокины</kwd><kwd>пептид LL-37</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Lee P.H., Ohtake T., Zaiou M., Murakami M., Rudisill J.A., Lin K.H., Gallo R.L. Expression of an additional cathelicidin antimicrobial peptide protects against bacterial skin infection. Proc. Natl. Acad. Sci. U S A. 2005; 102(10): 3750—5.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Будихина А.С., Макаров Е.А., Пинегин Б.В. Применение проточной цитометрии для оценки противомикробной активности кателицидина LL-37. 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