Russian Journal of Skin and Venereal DiseasesRussian Journal of Skin and Venereal Diseases1560-95882412-9097Eco-Vector10967810.17816/dv109678Research ArticleProblems of diagnostics of oral lichen planusGrabovskayaOlga V.<p>MD, Cand. Sci. (Med.), Professor</p>olgadoctor2013@yandex.ruhttps://orcid.org/0000-0002-5259-7481KayumovaLyailya N.<p>MD, Cand. Sci. (Med.), Assistant Lecturer</p>avestohka2005@inbox.ruhttps://orcid.org/0000-0003-0301-737XNikulinaAlena S.<p>MD, Graduate Student</p>a.niku@mail.ruhttps://orcid.org/0000-0002-0736-8022DamdinovaBaira<p>MD, Graduate Student</p>baira_d@mail.ruhttps://orcid.org/0000-0002-4162-2928ShakhmanovaSagibatSonya271195@yandex.ruhttps://orcid.org/0000-0001-8665-4731I.M. Sechenov First Moscow State Medical University131020222532292380808202213082022Copyright © 2022, Grabovskaya O.V., Kayumova L.N., Nikulina A.S., Damdinova B., Shakhmanova S.2022<p>Lichen planus is a disease most commonly found in both dermatological and dental practice. The etiology of this dermatosis is not fully understood. As a rule, with lichen planus, the organs of the gastrointestinal tract, cardiovascular, nervous, endocrine and other systems are affected. The disease can develop against the background of strong psychoemotional stress. Differential diagnosis of lichen planus is performed with leukoplakia, autoimmune pemphigus, candidiasis and lupus erythematosus.</p>
<p>The authors present their own clinical observation of a patient with a lichen planus of the oral mucosa, in whom a diagnostic error led to the series of unsuccessful hospitalizations, examinations, surgical interventions against the background of a gradual aggravation of the mental state.</p>
<p>The interest of this clinical observation is that in the case of diagnosis of lichen planus of the oral mucosa, a complete examination of the skin and all mucous membranes is necessary in order to identify the elements characteristic of this disease. Of particular importance is a biopsy with histological and immunohistochemical examination before the start of therapy. With a prolonged course of the disease, the ineffectiveness of invasive therapies requires timely administration of systemic glucocorticoids to achieve remission. Prolonged and persistent course of lichen planus of the oral mucosa can lead not only to the transformation of the process, but also to the development of psychogenic reactions.</p>
<p>The article shows the importance of a tandem between a dermatovenerologist, a dentist and a psychiatrist forthe effective care of patients with lesions of the oral mucosa with lichen planus.</p>lichen planusoral lichen planusa symptom of Wickham striaeкрасный плоский лишайкрасный плоский лишай слизистой оболочки ртасимптом сетки Уикхема[Chuikin S, Akmalova GM. Lichen planus of the oral mucosa: clinical forms and treatment. Kazan Med J. 2014;95(5):680–687. (In Russ).][Alrashdan MS, Cirillo N, McCullough M. Oral lichen planus: a literature review and update. Arch Dermatol Res. 2016;308(8): 539–551. doi: 10.1007/s00403-016-1667-2][Zhiltsova EE, Politov SA, Ermoshina NP, et al. Modern aspects of etiopathogenesis of lichen planus of the mucous membrane lining the oral cavity. In: Formation of public health: medical, social and clinical aspects: Collection of scientific papers. Ed. by O.E. Konovalov, S.V. Zhukov. Tver; 2020. Р. 76–81. (In Russ).][Cheng YS, Gould A, Kurago Z, et al. Diagnosis of oral lichen planus: a position paper of the American Academy of Oral and Maxillofacial Pathology. Oral Sur Oral Med Oral Pathology Oral Radiology. 2016;122(3):332–354. doi: 10.1016/j.oooo.2016.05.004][Clinical recommendations. Lichen is red flat. All-Russian public organization “Russian Society of Dermatovenerologists and Cosmetologists”; 2020. 34 p. (In Russ).][Molochkov VA, Amkhadova MA, Molochkova YV. Lichen planus of the oral cavity as an interdisciplinary problem. Med Alphabet. 2017;4(38):52–57. (In Russ).][Olisova OY, Teplyuk NP, Grabovskaya OV, Kolesova YV. Lichen planus. Russ J Skin Venereal Diseases. 2020;23(5):356–360. (In Russ). doi: 10.17816/dv59113][Serazetdinova AR, Trunin DA, Kirillova VP, et al. Analysis of a clinical case of a patient with red flat lichen of the oral mucosa associated with the Epstein-Barr virus. Actual Problems Dentistry. 2020;16(1):35–41. (In Russ). doi: 10.18481/2077-7566-20-16-1-35-41][Grigoriev SS, Zhovtyak PB, Letaeva OV. Oral lichen planus. Review. Ural Med J. 2014;5(119):8–15. (In Russ).][Vijayan AK, Muthukrishnan A, Vidyadharan M, Nair AM. Role of human papilloma virus in malignant transformation of oral lichen planus: a systematic review. J Pharm Bioallied Sci. 2021;13(Suppl 1):S62–S67. doi: 10.4103/jpbs.JPBS_836_20][Makeeva IM, Volkov AG, Dikopova NZ, Makarenko NV. The determination of electrochemical potentials in the oral cavity, as a method of diagnosing galvanic syndrome contributing to the development of diseases of the mucous membrane. Head Neck. 2018;(1):42–45. (In Russ). doi: 10.25792/HN.2018.6.1.42–45][Martin MD, Broughton S, Drangsholt M. Oral lichen plantus and dental materials: a case-control study. Contact Dermatitis. 2003;48(6):331–336. doi: 10.1034/j.1600-0536.2003.00146.x][Tiunova NV. Lichen planus: choice of treatment method. Review. Dentistry. 2011;1(72):14–15. (In Russ).][Dorozhenok IY, Snarskaya ES, Mikhailova M. Lichen planus and itch-related psychosomatic disorders. Russ J Skin Venereal Diseases. 2021;24(6):543–551. doi: 10.17816/dv100612][Hanova SA, Sirak SV, Chebotarev VV, Sirak AG. Lichen planus of the oral mucosa, modern methods of local treatment. Int J Applied Fundamental Res. 2014;(2):197–202. (In Russ).][Skin and venereal diseases: textbook. Ed. by O.Yu. Olisova. Moscow: Practical Medicine; 2015. 288 p. (In Russ).][Kurago ZB. Etiology and pathogenesis of oral lichen planus: an overview. Oral Sur Oral Med Oral Pathology Oral Radiology. 2016;122(1):72–80. doi: 10.1016/j.oooo.2016.03.011][Chiang CP, Chang JY, Wang YP, et al. Oral lichen planus ― differential diagnoses, serum autoantibodies, hematinic deficiencies, and management. J Formosan Med Association. 2018;117(9):756–765. doi: 10.1016/j.jfma.2018.01.021][Red lichen planus of the oral mucosa. Clinic, diagnosis, treatment and prevention. Methodological recommendations. Department of Health of Moscow; 2021. 27 p. (In Russ).]