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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Skin and Venereal Diseases</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Skin and Venereal Diseases</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский журнал кожных и венерических болезней</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1560-9588</issn><issn publication-format="electronic">2412-9097</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">108631</article-id><article-id pub-id-type="doi">10.17816/dv108631</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DERMATOLOGY</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДЕРМАТОЛОГИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Clinical and epidemiological features of psoriasis in the Republic of Uzbekistan</article-title><trans-title-group xml:lang="ru"><trans-title>Клинико-эпидемиологические особенности псориаза в Республике Узбекистан</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2482-1754</contrib-id><contrib-id contrib-id-type="spin">2500-7989</contrib-id><name-alternatives><name xml:lang="en"><surname>Olisova</surname><given-names>Olga Yu.</given-names></name><name xml:lang="ru"><surname>Олисова</surname><given-names>Ольга Юрьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>olisovaolga@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0404-779X</contrib-id><name-alternatives><name xml:lang="en"><surname>Melikova</surname><given-names>Nigina I.</given-names></name><name xml:lang="ru"><surname>Меликова</surname><given-names>Нигина Исраиловна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Graduate Student</p></bio><bio xml:lang="ru"><p>аспирант</p></bio><email>niginamelikova29@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4380-6982</contrib-id><contrib-id contrib-id-type="spin">7902-5210</contrib-id><name-alternatives><name xml:lang="en"><surname>Tashkenbaeva</surname><given-names>Umida A.</given-names></name><name xml:lang="ru"><surname>Ташкенбаева</surname><given-names>Умида Алишеровна</given-names></name></name-alternatives><address><country country="UZ">Uzbekistan</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Associate Professor</p></bio><bio xml:lang="ru"><p>д.м.н., доцент</p></bio><email>umidatashkenbaeva@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3835-0842</contrib-id><contrib-id contrib-id-type="spin">7797-0908</contrib-id><name-alternatives><name xml:lang="en"><surname>Torchinskiy</surname><given-names>Nikolay V.</given-names></name><name xml:lang="ru"><surname>Торчинский</surname><given-names>Николай Викторович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.), Associate Professor</p></bio><bio xml:lang="ru"><p>к.м.н., доцент</p></bio><email>torchinsky75@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution></aff><aff><institution xml:lang="ru">Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет)</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Tashkent Medical Academy</institution></aff><aff><institution xml:lang="ru">Ташкентская медицинская академия</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-08-23" publication-format="electronic"><day>23</day><month>08</month><year>2022</year></pub-date><volume>25</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>127</fpage><lpage>132</lpage><history><date date-type="received" iso-8601-date="2022-06-08"><day>08</day><month>06</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-06-30"><day>30</day><month>06</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, ООО "Эко-Вектор"</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2025-08-01"/></permissions><self-uri xlink:href="https://rjsvd.com/1560-9588/article/view/108631">https://rjsvd.com/1560-9588/article/view/108631</self-uri><abstract xml:lang="en"><p><italic>BACKGROUND:</italic> Psoriasis is one of the most common dermatoses. The disease has a negative impact on every aspect of the patient’s life ― social, physical and psychological. Psoriasis is accompanied by a marked deterioration in the quality of life of patients, which often leads to their social maladaptation.</p> <p><italic>AIMS:</italic> This study is aimed at assessing the nature of epidemiological and clinical manifestations of psoriasis in the Republic of Uzbekistan.</p> <p><italic>MATERIALS AND METHODS:</italic> The data of the population register of psoriatic diseases created on the basis of the Republican Skin and Venereological Clinical Hospital the city of Tashkent, the Republican Specialized Scientific and Practical Center of Dermatology and Cosmetology of the Republic of Uzbekistan were studied. A retrospective analysis of case histories for the period 2015–2019 was also carried out at the clinical base of the Department of Dermatovenerology of the Tashkent Medical Academy.</p> <p><italic>RESULTS:</italic> The prevalence of psoriasis among the general population of the Republic of Uzbekistan from 2010 to 2020 during the study period significantly increased, especially in the age group of 15–29 years. Men suffer from psoriasis more often, this disease is characterized by an earlier onset of the disease (age group up to 40 years). The most common clinical form of psoriasis is vulgar psoriasis.</p> <p><italic>CONCLUSIONS:</italic> There is a clear need to improve the quality and increase the amount of data related to the epidemiology of psoriasis in the Republic of Uzbekistan. Diagnostic criteria and reports on morbidity and prevalence should be standardized.</p></abstract><trans-abstract xml:lang="ru"><p><italic>Обоснование.</italic> Псориаз является одним из наиболее распространённых дерматозов. Заболевание оказывает негативное влияние на каждую сторону жизни пациента ― социальную, физическую и психологическую. Псориаз сопровождается выраженным ухудшением качества жизни пациентов, что зачастую приводит к их социальной дезадаптации.</p> <p><italic>Цель</italic> ― оценка характера эпидемиологических и клинических проявлений псориаза в Республике Узбекистан.</p> <p><italic>Материал и методы. </italic>Изучены данные популяционного регистра псориатических заболеваний, созданного на базе Республиканской кожно-венерологической клинической больницы города Ташкента, Республиканского специализированного научно-практического центра дерматологии и косметологии Республики Узбекистан. Ретроспективный анализ историй болезни за период 2015–2019 гг. проведён на клинической базе кафедры дерматовенерологии Ташкентской медицинской академии.</p> <p><italic>Результаты.</italic> Распространённость псориаза среди общего населения Республики Узбекистан с 2010 по 2020 г. достоверно увеличилась, особенно в возрастной группе 15–29 лет. Псориазом чаще страдают мужчины, для заболевания характерно раннее начало (возрастная группа до 40 лет). Наиболее частой клинической формой является вульгарный псориаз.</p> <p><italic>Заключение. </italic>Существует явная потребность в улучшении качества и увеличении количества данных, касающихся эпидемиологии псориаза в Республике Узбекистан. Диагностические критерии и отчёты о заболеваемости и распространённости должны быть стандартизированы.</p></trans-abstract><kwd-group xml:lang="en"><kwd>psoriasis</kwd><kwd>epidemiology</kwd><kwd>risk factor</kwd><kwd>Republic of Uzbekistan</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>псориаз</kwd><kwd>сопутствующие заболевания</kwd><kwd>эпидемиология</kwd><kwd>фактор риска</kwd><kwd>Республика Узбекистан</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Kuchekar AB, Pujari RR, Kuchekar SB, et al. Psoriasis: a comprehensive review. Int J Pharm Life Sci. 2011;2(6):857–877.</mixed-citation><mixed-citation xml:lang="ru">Kuchekar A.B., Pujari R.R., Kuchekar S.B., et al. Psoriasis: a comprehensive review // Int J Pharm Life Sci. 2011. Vol. 2, N 6. 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